| http://purl.uniprot.org/citations/19185848 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19185848 | http://www.w3.org/2000/01/rdf-schema#comment | "The growth of many cancers depends on self-renewing cells called cancer stem cells or tumor-propagating cells (TPCs). In human brain tumors, cells expressing the stem cell marker CD133 have been implicated as TPCs. Here we show that tumors from a model of medulloblastoma, the Patched mutant mouse, are propagated not by CD133(+) cells but by cells expressing the progenitor markers Math1 and CD15/SSEA-1. These cells have a distinct expression profile that suggests increased proliferative capacity and decreased tendency to undergo apoptosis and differentiation. CD15 is also found in a subset of human medulloblastomas, and tumors expressing genes similar to those found in murine CD15(+) cells have a poorer prognosis. Thus, CD15 may represent an important marker for TPCs in medulloblastoma."xsd:string |
| http://purl.uniprot.org/citations/19185848 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ccr.2008.12.016"xsd:string |
| http://purl.uniprot.org/citations/19185848 | http://purl.uniprot.org/core/author | "Wei Z."xsd:string |
| http://purl.uniprot.org/citations/19185848 | http://purl.uniprot.org/core/author | "Ellison D.W."xsd:string |
| http://purl.uniprot.org/citations/19185848 | http://purl.uniprot.org/core/author | "Wechsler-Reya R.J."xsd:string |
| http://purl.uniprot.org/citations/19185848 | http://purl.uniprot.org/core/author | "Markant S.L."xsd:string |
| http://purl.uniprot.org/citations/19185848 | http://purl.uniprot.org/core/author | "McLendon R.E."xsd:string |
| http://purl.uniprot.org/citations/19185848 | http://purl.uniprot.org/core/author | "Fogarty M.P."xsd:string |
| http://purl.uniprot.org/citations/19185848 | http://purl.uniprot.org/core/author | "Febbo P.G."xsd:string |
| http://purl.uniprot.org/citations/19185848 | http://purl.uniprot.org/core/author | "Read T.A."xsd:string |
| http://purl.uniprot.org/citations/19185848 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19185848 | http://purl.uniprot.org/core/name | "Cancer Cell"xsd:string |
| http://purl.uniprot.org/citations/19185848 | http://purl.uniprot.org/core/pages | "135-147"xsd:string |
| http://purl.uniprot.org/citations/19185848 | http://purl.uniprot.org/core/title | "Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma."xsd:string |
| http://purl.uniprot.org/citations/19185848 | http://purl.uniprot.org/core/volume | "15"xsd:string |
| http://purl.uniprot.org/citations/19185848 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19185848 |
| http://purl.uniprot.org/citations/19185848 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19185848 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YVW7-mappedCitation-19185848 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19185848 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YVX7-mappedCitation-19185848 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19185848 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YWC4-mappedCitation-19185848 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19185848 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YWZ4-mappedCitation-19185848 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19185848 |
| http://purl.uniprot.org/uniprot/#_B2RPT3-mappedCitation-19185848 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19185848 |
| http://purl.uniprot.org/uniprot/#_P48985-mappedCitation-19185848 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19185848 |
| http://purl.uniprot.org/uniprot/#_Q11127-mappedCitation-19185848 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19185848 |