http://purl.uniprot.org/citations/19188444 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19188444 | http://www.w3.org/2000/01/rdf-schema#comment | "Dosage compensation equalizes X-linked gene products between the sexes. In Caenorhabditis elegans, the dosage compensation complex (DCC) binds both X chromosomes in XX animals and halves the transcription from each. The DCC is recruited to the X chromosomes by a number of loci, rex sites, and is thought to spread from these sites by an unknown mechanism to cover the rest of the chromosome. Here we describe a novel class of DCC-binding elements that we propose serve as "way stations" for DCC binding and spreading. Both rex sites and way stations comprise strong foci of DCC binding on the native X chromosome. However, rex sites maintain their ability to bind large amounts of DCC even on X duplications detached from the native X, while way stations do not. These results suggest that two distinct classes of DCC-binding elements facilitate recruitment and spreading of the DCC along the X chromosome."xsd:string |
http://purl.uniprot.org/citations/19188444 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.01448-08"xsd:string |
http://purl.uniprot.org/citations/19188444 | http://purl.uniprot.org/core/author | "Csankovszki G."xsd:string |
http://purl.uniprot.org/citations/19188444 | http://purl.uniprot.org/core/author | "Blauwkamp T.A."xsd:string |
http://purl.uniprot.org/citations/19188444 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19188444 | http://purl.uniprot.org/core/name | "Mol Cell Biol"xsd:string |
http://purl.uniprot.org/citations/19188444 | http://purl.uniprot.org/core/pages | "2023-2031"xsd:string |
http://purl.uniprot.org/citations/19188444 | http://purl.uniprot.org/core/title | "Two classes of dosage compensation complex binding elements along Caenorhabditis elegans X chromosomes."xsd:string |
http://purl.uniprot.org/citations/19188444 | http://purl.uniprot.org/core/volume | "29"xsd:string |
http://purl.uniprot.org/citations/19188444 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19188444 |
http://purl.uniprot.org/citations/19188444 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19188444 |
http://purl.uniprot.org/uniprot/G5EFJ4#attribution-F7A473F00D76132ECFB0AF4B53F55D63 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19188444 |
http://purl.uniprot.org/uniprot/G5EFJ4#attribution-F7D057BEBC076A2C312BD49F848400AC | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19188444 |
http://purl.uniprot.org/uniprot/Q9U2M1#attribution-F7D057BEBC076A2C312BD49F848400AC | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19188444 |
http://purl.uniprot.org/uniprot/G5EGE9#attribution-F7D057BEBC076A2C312BD49F848400AC | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19188444 |
http://purl.uniprot.org/uniprot/P34341#attribution-F7D057BEBC076A2C312BD49F848400AC | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19188444 |
http://purl.uniprot.org/uniprot/Q20060#attribution-F7D057BEBC076A2C312BD49F848400AC | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19188444 |
http://purl.uniprot.org/uniprot/Q20818#attribution-F7D057BEBC076A2C312BD49F848400AC | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19188444 |
http://purl.uniprot.org/uniprot/#_P34341-mappedCitation-19188444 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19188444 |
http://purl.uniprot.org/uniprot/#_G5EFJ4-mappedCitation-19188444 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19188444 |
http://purl.uniprot.org/uniprot/#_G5EGE9-mappedCitation-19188444 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19188444 |
http://purl.uniprot.org/uniprot/#_Q20060-mappedCitation-19188444 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19188444 |
http://purl.uniprot.org/uniprot/#_Q20818-mappedCitation-19188444 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19188444 |
http://purl.uniprot.org/uniprot/#_Q9U2M1-mappedCitation-19188444 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19188444 |