http://purl.uniprot.org/citations/19193991 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19193991 | http://www.w3.org/2000/01/rdf-schema#comment | "The binding of (+)-camphor to cytochrome P450cam (P450cam) expels a cluster of waters at the active site, raising the redox potential of the haem to an extent that allows reduction by the electron-transfer system. This binding was reported to involve no significant structural changes in the protein. Here, two ferric P450cam structures partially complexed with (+)-camphor were determined by X-ray crystallography at 1.30-1.35 A resolution, revealing the structures of the substrate-free and substrate-bound forms. (+)-Camphor binding induces rotation of Thr101 to form a hydrogen bond that acts as a hydrogen donor to a peripheral haem propionate. This bonding contributes to the redox-potential change."xsd:string |
http://purl.uniprot.org/citations/19193991 | http://purl.org/dc/terms/identifier | "doi:10.1107/s1744309108044114"xsd:string |
http://purl.uniprot.org/citations/19193991 | http://purl.uniprot.org/core/author | "Hayashi T."xsd:string |
http://purl.uniprot.org/citations/19193991 | http://purl.uniprot.org/core/author | "Tsukihara T."xsd:string |
http://purl.uniprot.org/citations/19193991 | http://purl.uniprot.org/core/author | "Shimada H."xsd:string |
http://purl.uniprot.org/citations/19193991 | http://purl.uniprot.org/core/author | "Sakurai K."xsd:string |
http://purl.uniprot.org/citations/19193991 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19193991 | http://purl.uniprot.org/core/name | "Acta Crystallogr Sect F Struct Biol Cryst Commun"xsd:string |
http://purl.uniprot.org/citations/19193991 | http://purl.uniprot.org/core/pages | "80-83"xsd:string |
http://purl.uniprot.org/citations/19193991 | http://purl.uniprot.org/core/title | "Substrate binding induces structural changes in cytochrome P450cam."xsd:string |
http://purl.uniprot.org/citations/19193991 | http://purl.uniprot.org/core/volume | "65"xsd:string |
http://purl.uniprot.org/citations/19193991 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19193991 |
http://purl.uniprot.org/citations/19193991 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19193991 |
http://purl.uniprot.org/uniprot/#_P00183-mappedCitation-19193991 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19193991 |
http://purl.uniprot.org/uniprot/P00183 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19193991 |