| http://purl.uniprot.org/citations/19201479 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19201479 | http://www.w3.org/2000/01/rdf-schema#comment | "Complement receptor proteins CR2 (CD21) and CR1 (CD35) have been identified as components of the murine B cell co-receptor complex. Gene expression profiles between naïve WT, C3-/-, and CD21/35-/-B cells demonstrate enhanced expression of a Ca(2+)-modulating gene, Pcp4, in WT mice compared to the complement-deficient animals. Increased expression of Pcp4 is also coincident with B cell maturation into end stage phenotypes. Prolonged activation of B cells via cross-linking of the BCR (but not CR1/CR2 alone) leads to increased expression of Pcp4 and suppressed Ca(2+) release. In total these data demonstrate that the expression of Pcp4 in naïve resting mature B cells is dependent upon tonic stimulation from the CR1/CR2 proteins via a C3 ligand, and that antigen specific B cell activation can also elevate Pcp4 expression that is coincident with suppression of calcium-dependent responses."xsd:string |
| http://purl.uniprot.org/citations/19201479 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.molimm.2008.12.030"xsd:string |
| http://purl.uniprot.org/citations/19201479 | http://purl.uniprot.org/core/author | "Weis J.H."xsd:string |
| http://purl.uniprot.org/citations/19201479 | http://purl.uniprot.org/core/author | "Weis J.J."xsd:string |
| http://purl.uniprot.org/citations/19201479 | http://purl.uniprot.org/core/author | "Jacobson A.C."xsd:string |
| http://purl.uniprot.org/citations/19201479 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19201479 | http://purl.uniprot.org/core/name | "Mol Immunol"xsd:string |
| http://purl.uniprot.org/citations/19201479 | http://purl.uniprot.org/core/pages | "1488-1493"xsd:string |
| http://purl.uniprot.org/citations/19201479 | http://purl.uniprot.org/core/title | "CD21 signaling via C3 regulates Purkinje cell protein 4 expression."xsd:string |
| http://purl.uniprot.org/citations/19201479 | http://purl.uniprot.org/core/volume | "46"xsd:string |
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