http://purl.uniprot.org/citations/19216560 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19216560 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19216560 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
http://purl.uniprot.org/citations/19216560 | http://www.w3.org/2000/01/rdf-schema#comment | "Details of the fungal biosynthetic pathway to helvolic acid and other fusidane antibiotics remain obscure. During product characterization of oxidosqualene cyclases in Aspergillus fumigatus, we found the long-sought cyclase that makes (17Z)-protosta-17(20),24-dien-3beta-ol, the precursor of helvolic acid. We then identified a gene cluster encoding the pathway to helvolic acid, which is controlled by a transcription regulator (LaeA) associated with fungal virulence. Evidence regarding the evolutionary origin and taxonomic distribution of fusidane biosynthesis is also presented."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.org/dc/terms/identifier | "doi:10.1021/ol802696a"xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.org/dc/terms/identifier | "doi:10.1021/ol802696a"xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/author | "Smith M.L."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/author | "Smith M.L."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/author | "Wilson W.K."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/author | "Wilson W.K."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/author | "May G.S."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/author | "May G.S."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/author | "Xiong Q."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/author | "Xiong Q."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/author | "Lodeiro S."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/author | "Lodeiro S."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/author | "Matsuda S.P."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/author | "Matsuda S.P."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/author | "Ivanova Y."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/author | "Ivanova Y."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/name | "Org. Lett."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/name | "Org. Lett."xsd:string |
http://purl.uniprot.org/citations/19216560 | http://purl.uniprot.org/core/pages | "1241-1244"xsd:string |