| http://purl.uniprot.org/citations/19220457 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19220457 | http://www.w3.org/2000/01/rdf-schema#comment | "Talins are large adaptor proteins that link the integrin family of adhesion molecules to F-actin. In vertebrates, there are two talin genes. Talin 1 is essential for integrin-mediated cell adhesion; the role of talin 2 is unclear. Here we report a detailed analysis of mammalian talin 2. This reveals the existence of a previously unrecognized promoter associated with a CpG island, and separated from the first coding exon by numerous alternatively spliced noncoding exons spanning > 200 kb. Analysis of a mouse gene trap line shows that this promoter accounts for most of the talin 2 expression in adult tissues. We also demonstrate that testis and kidney express truncated talin 2 isoforms that lack the N-terminal half of the protein, and provide evidence for the developmentally regulated expression of the short testis-specific talin 2 isoform in elongating spermatids. Finally, we identify four tissue-specific alternative splicing events within the coding region of talin 2."xsd:string |
| http://purl.uniprot.org/citations/19220457 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1742-4658.2009.06893.x"xsd:string |
| http://purl.uniprot.org/citations/19220457 | http://purl.uniprot.org/core/author | "Bate N."xsd:string |
| http://purl.uniprot.org/citations/19220457 | http://purl.uniprot.org/core/author | "Critchley D.R."xsd:string |
| http://purl.uniprot.org/citations/19220457 | http://purl.uniprot.org/core/author | "Praekelt U."xsd:string |
| http://purl.uniprot.org/citations/19220457 | http://purl.uniprot.org/core/author | "Debrand E."xsd:string |
| http://purl.uniprot.org/citations/19220457 | http://purl.uniprot.org/core/author | "Monkley S.J."xsd:string |
| http://purl.uniprot.org/citations/19220457 | http://purl.uniprot.org/core/author | "Pritchard C.A."xsd:string |
| http://purl.uniprot.org/citations/19220457 | http://purl.uniprot.org/core/author | "El Jai Y."xsd:string |
| http://purl.uniprot.org/citations/19220457 | http://purl.uniprot.org/core/author | "Spence L."xsd:string |
| http://purl.uniprot.org/citations/19220457 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19220457 | http://purl.uniprot.org/core/name | "FEBS J"xsd:string |
| http://purl.uniprot.org/citations/19220457 | http://purl.uniprot.org/core/pages | "1610-1628"xsd:string |
| http://purl.uniprot.org/citations/19220457 | http://purl.uniprot.org/core/title | "Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms."xsd:string |
| http://purl.uniprot.org/citations/19220457 | http://purl.uniprot.org/core/volume | "276"xsd:string |
| http://purl.uniprot.org/citations/19220457 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19220457 |
| http://purl.uniprot.org/citations/19220457 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19220457 |
| http://purl.uniprot.org/uniprot/#_A0A1L1SVA8-mappedCitation-19220457 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19220457 |
| http://purl.uniprot.org/uniprot/#_A0A1L1SQ51-mappedCitation-19220457 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19220457 |
| http://purl.uniprot.org/uniprot/#_A0A1L1SQP9-mappedCitation-19220457 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19220457 |
| http://purl.uniprot.org/uniprot/#_A0A1L1SRI1-mappedCitation-19220457 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19220457 |
| http://purl.uniprot.org/uniprot/#_B2RY15-mappedCitation-19220457 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19220457 |
| http://purl.uniprot.org/uniprot/#_E9PUM4-mappedCitation-19220457 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19220457 |
| http://purl.uniprot.org/uniprot/#_Q71LX4-mappedCitation-19220457 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19220457 |