RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/19229337http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19229337http://www.w3.org/2000/01/rdf-schema#comment"Rx is a paired-like homeobox gene that is required for vertebrate eye formation. Mice lacking Rx function do not develop eyes or the posterior pituitary. To determine whether Rx is required cell autonomously in these tissues, we generated embryonic chimeras consisting of wild type and Rx-/-cells. We found that in the eye, Rx-deficient cells cannot participate in the formation of the neuroretina, retina pigment epithelium and the distal part of the optic stalk. In addition, in the ventral forebrain, Rx function is required cell autonomously for the formation of the posterior pituitary. Interestingly, Rx-/- and wild type cells segregate before the morphogenesis of these two tissues begins. Our observations suggest that Rx function is not only required for the morphogenesis of the retina and posterior pituitary, but also prior to morphogenesis, for the sorting out of cells to form distinct fields of retinal/pituitary cells."xsd:string
http://purl.uniprot.org/citations/19229337http://purl.org/dc/terms/identifier"doi:10.1371/journal.pone.0004513"xsd:string
http://purl.uniprot.org/citations/19229337http://purl.uniprot.org/core/author"Liu C."xsd:string
http://purl.uniprot.org/citations/19229337http://purl.uniprot.org/core/author"Shah R."xsd:string
http://purl.uniprot.org/citations/19229337http://purl.uniprot.org/core/author"Zhang L."xsd:string
http://purl.uniprot.org/citations/19229337http://purl.uniprot.org/core/author"Behringer R.R."xsd:string
http://purl.uniprot.org/citations/19229337http://purl.uniprot.org/core/author"Mendoza M."xsd:string
http://purl.uniprot.org/citations/19229337http://purl.uniprot.org/core/author"Jamrich M."xsd:string
http://purl.uniprot.org/citations/19229337http://purl.uniprot.org/core/author"Mahon K.A."xsd:string
http://purl.uniprot.org/citations/19229337http://purl.uniprot.org/core/author"Amaya-Manzanares F."xsd:string
http://purl.uniprot.org/citations/19229337http://purl.uniprot.org/core/author"Medina-Martinez O."xsd:string
http://purl.uniprot.org/citations/19229337http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19229337http://purl.uniprot.org/core/name"PLoS One"xsd:string
http://purl.uniprot.org/citations/19229337http://purl.uniprot.org/core/pages"e4513"xsd:string
http://purl.uniprot.org/citations/19229337http://purl.uniprot.org/core/title"Cell-autonomous requirement for rx function in the mammalian retina and posterior pituitary."xsd:string
http://purl.uniprot.org/citations/19229337http://purl.uniprot.org/core/volume"4"xsd:string
http://purl.uniprot.org/citations/19229337http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19229337
http://purl.uniprot.org/citations/19229337http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19229337
http://purl.uniprot.org/uniprot/#_A2ALD8-mappedCitation-19229337http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19229337
http://purl.uniprot.org/uniprot/#_A0A494B9Q2-mappedCitation-19229337http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19229337
http://purl.uniprot.org/uniprot/#_A0A494BBH8-mappedCitation-19229337http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19229337
http://purl.uniprot.org/uniprot/#_A0A494BB35-mappedCitation-19229337http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19229337
http://purl.uniprot.org/uniprot/#_B2RSE8-mappedCitation-19229337http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19229337
http://purl.uniprot.org/uniprot/#_O35565-mappedCitation-19229337http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19229337