| http://purl.uniprot.org/citations/19234459 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19234459 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19234459 | http://www.w3.org/2000/01/rdf-schema#comment | "Although the properties and trafficking of AMPA-type glutamate receptors (AMPARs) depend critically on associated transmembrane AMPAR regulatory proteins (TARPs) such as stargazin (gamma-2), no TARP has been described that can specifically regulate the important class of calcium-permeable (CP-) AMPARs. We examined the stargazin-related protein gamma-5, which is highly expressed in Bergmann glia, a cell type possessing only CP-AMPARs. gamma-5 was previously thought not to be a TARP, and it has been widely used as a negative control. Here we find that, contrary to expectation, gamma-5 acts as a TARP and serves this role in Bergmann glia. Whereas gamma-5 interacts with all AMPAR subunits, and modifies their behavior to varying extents, its main effect is to regulate the function of AMPAR subunit combinations that lack short-form subunits, which constitute predominantly CP-AMPARs. Our results suggest an important role for gamma-5 in regulating the functional contribution of CP-AMPARs."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.org/dc/terms/identifier | "doi:10.1038/nn.2266"xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.org/dc/terms/identifier | "doi:10.1038/nn.2266"xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/author | "Coombs I.D."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/author | "Coombs I.D."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/author | "Cull-Candy S.G."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/author | "Cull-Candy S.G."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/author | "Farrant M."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/author | "Farrant M."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/author | "Renzi M."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/author | "Renzi M."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/author | "Soto D."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/author | "Soto D."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/author | "Zonouzi M."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/author | "Zonouzi M."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/name | "Nat. Neurosci."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/name | "Nat. Neurosci."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/pages | "277-285"xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/pages | "277-285"xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/title | "Selective regulation of long-form calcium-permeable AMPA receptors by an atypical TARP, gamma-5."xsd:string |
| http://purl.uniprot.org/citations/19234459 | http://purl.uniprot.org/core/title | "Selective regulation of long-form calcium-permeable AMPA receptors by an atypical TARP, gamma-5."xsd:string |