http://purl.uniprot.org/citations/19249230 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19249230 | http://www.w3.org/2000/01/rdf-schema#comment | "Immunity to the intestinal parasite Heligomosomoides polygyrus is dependent on the successful generation of T helper 2 (Th2) memory cells. We showed that B cells contribute to immunity against H. polygyrus by producing antibody (Ab) and by promoting expansion and differentiation of primary and memory Th2 cells. We also demonstrated that cytokine-producing effector B cells were essential for effective immunity to H. polygyrus. Tumor necrosis factor alpha production by B cells was necessary for sustained Ab production, whereas interleukin 2 production by B cells was necessary for Th2 cell expansion and differentiation. These results show that B cells mediate protection from pathogens not only by presenting antigen and secreting antibody but also by producing cytokines that regulate the quality and magnitude of humoral and cellular immune responses."xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.immuni.2009.01.006"xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/author | "Harris D.P."xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/author | "Honjo T."xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/author | "Mousseau B."xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/author | "Lund F.E."xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/author | "Makris M."xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/author | "Kusser K."xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/author | "Randall T."xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/author | "Wojciechowski W."xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/author | "Mohrs M."xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/author | "Mohrs K."xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/author | "Sprague F."xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/pages | "421-433"xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/title | "Cytokine-producing effector B cells regulate type 2 immunity to H. polygyrus."xsd:string |
http://purl.uniprot.org/citations/19249230 | http://purl.uniprot.org/core/volume | "30"xsd:string |
http://purl.uniprot.org/citations/19249230 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19249230 |
http://purl.uniprot.org/citations/19249230 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19249230 |
http://purl.uniprot.org/uniprot/#_A0A0U1RNW1-mappedCitation-19249230 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19249230 |
http://purl.uniprot.org/uniprot/#_A0A075B5P6-mappedCitation-19249230 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19249230 |
http://purl.uniprot.org/uniprot/#_A0A075B6A0-mappedCitation-19249230 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19249230 |
http://purl.uniprot.org/uniprot/#_E0CXQ9-mappedCitation-19249230 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19249230 |