| http://purl.uniprot.org/citations/19254694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19254694 | http://www.w3.org/2000/01/rdf-schema#comment | "Signal transducer and activator of transcription 3 (STAT3), which is activated by cytokines and growth factors, mediates biological actions in many physiological processes. In a previous study, we found that Y14, a core component of the exon-junction complex (EJC) bound to STAT3 and upregulated the transcriptional activity of STAT3 by influencing its DNA-binding activity. In the present study, we demonstrate that STAT3 endogenously interacts with Y14. In addition, we found that MAGOH, a Y14 partner in the EJC, inhibits the STAT3-Y14 complex formation. Furthermore, small-interfering RNA-mediated reduction of MAGOH expression enhanced interleukin-6-induced gene expression. These results indicate that MAGOH regulates the transcriptional activation of STAT3 by interfering complex formation between STAT3 and Y14."xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2009.02.127"xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/author | "Kawakami S."xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/author | "Shiga K."xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/author | "Matsuda T."xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/author | "Kamitani S."xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/author | "Oritani K."xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/author | "Nanbo A."xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/author | "Ikeda O."xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/author | "Muromoto R."xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/author | "Sekine Y."xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/author | "Taira N."xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/author | "Togi S."xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/pages | "63-68"xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/title | "The exon-junction complex proteins, Y14 and MAGOH regulate STAT3 activation."xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://purl.uniprot.org/core/volume | "382"xsd:string |
| http://purl.uniprot.org/citations/19254694 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19254694 |
| http://purl.uniprot.org/citations/19254694 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19254694 |
| http://purl.uniprot.org/uniprot/#_A0A060D9J6-mappedCitation-19254694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19254694 |
| http://purl.uniprot.org/uniprot/#_A0A023T787-mappedCitation-19254694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19254694 |
| http://purl.uniprot.org/uniprot/#_A0A7I2V395-mappedCitation-19254694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19254694 |
| http://purl.uniprot.org/uniprot/#_B4DNP0-mappedCitation-19254694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19254694 |