| http://purl.uniprot.org/citations/19264783 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19264783 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19264783 | http://www.w3.org/2000/01/rdf-schema#comment | "nsp1 protein of severe acute respiratory syndrome coronavirus (SARS-CoV), a group 2b CoV, suppresses host gene expression by promoting host mRNA degradation and translation inhibition. The present study analyzed the activities of nsp1 proteins from the group 2 bat CoV strains Rm1, 133, and HKU9-1, belonging to groups 2b, 2c, and 2d, respectively. The host mRNA degradation and translational suppression activities of nsp1 of SARS-CoV and Rm1 nsp1 were similar and stronger than the activities of the nsp1 proteins of 133 and HKU9-1. Rm1 nsp1 expression in trans strongly inhibited the induction of type I interferon (IFN-I) and IFN-stimulated genes in cells infected with an IFN-inducing SARS-CoV mutant, while 133 and HKU9-1 nsp1 proteins had relatively moderate IFN-inhibitory activities. The results of our studies suggested a conserved function among nsp1 proteins of SARS-CoV and group 2 bat CoVs."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.org/dc/terms/identifier | "doi:10.1128/jvi.02485-08"xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.org/dc/terms/identifier | "doi:10.1128/jvi.02485-08"xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/author | "Makino S."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/author | "Makino S."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/author | "Huang C."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/author | "Huang C."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/author | "Narayanan K."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/author | "Narayanan K."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/author | "Tohya Y."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/author | "Tohya Y."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/author | "Kamitani W."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/author | "Kamitani W."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/author | "Lokugamage K."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/author | "Lokugamage K."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/name | "J. Virol."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/name | "J. Virol."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/pages | "5282-5288"xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/pages | "5282-5288"xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/title | "Suppression of host gene expression by nsp1 proteins of group 2 bat coronaviruses."xsd:string |
| http://purl.uniprot.org/citations/19264783 | http://purl.uniprot.org/core/title | "Suppression of host gene expression by nsp1 proteins of group 2 bat coronaviruses."xsd:string |