| http://purl.uniprot.org/citations/19272325 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19272325 | http://www.w3.org/2000/01/rdf-schema#comment | "We investigated the association of human leukocyte antigen (HLA) II (DRB1 and DQB1) alleles with susceptibility to human papillomavirus (HPV)-associated cervical precancer and cancer cases in a hospital-based case-control study in a northern Indian population. A total of 202 subjects, including 100 patients comprising 31 cervical precancer (cervical intraepithelial neoplasia [CIN] 2/3) and 69 invasive cervical cancer cases, and 102 healthy controls participated in the study. Both patients and controls were screened for HPV infection using a polymerase chain reaction (PCR-based approach. Low-resolution PCR-sequence specific priming (PCR-SSP) was used to genotype HLA II (DRB1 and DQB1). Our results demonstrate that the DRB1*15 allele/DRB1*15-DQB1*06 haplotype may have a predisposition for HPV infection (p(c) < 0.05) or cervical cancer/precancer (p(c) < 0.05) development, whereas the DRB1*04 allele/DRB1*04-DQB1*03 haplotype might exhibit susceptibility to cervical precancerous lesions (p(c) < 0.05). The DRB1*13 allele/DRB1*13-DQB1*06 haplotype was strongly protective against risk to HPV infection (p(c) < 0.002) as well as cervical cancer (p(c) 0.01). Therefore, we have demonstrated that HLA DR-DQ polymorphisms are involved in genetic susceptibility to cervical cancer or HPV infection in a northern Indian population."xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.humimm.2009.01.003"xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/author | "Singh V."xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/author | "Hussain S."xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/author | "Thakur N."xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/author | "Das B.C."xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/author | "Tiwari P."xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/author | "Bharadwaj M."xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/author | "Batra S."xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/author | "Kohaar I."xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/author | "Sarkar D.P."xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/author | "Nasare V."xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/author | "Bhambani S."xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/name | "Hum Immunol"xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/pages | "222-229"xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/title | "Association between human leukocyte antigen class II alleles and human papillomavirus-mediated cervical cancer in Indian women."xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://purl.uniprot.org/core/volume | "70"xsd:string |
| http://purl.uniprot.org/citations/19272325 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19272325 |
| http://purl.uniprot.org/citations/19272325 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19272325 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-19272325 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19272325 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-19272325 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19272325 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-19272325 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19272325 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DC97-mappedCitation-19272325 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19272325 |