| http://purl.uniprot.org/citations/19279206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19279206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19279206 | http://www.w3.org/2000/01/rdf-schema#comment | "In the war against Plasmodium, humans have evolved to eliminate or modify proteins on the erythrocyte surface that serve as receptors for parasite invasion, such as the Duffy blood group, a receptor for Plasmodium vivax, and the Gerbich-negative modification of glycophorin C for Plasmodium falciparum. In turn, the parasite counters with expansion and diversification of ligand families. The high degree of polymorphism in glycophorin B found in malaria-endemic regions suggests that it also may be a receptor for Plasmodium, but, to date, none has been identified. We provide evidence from erythrocyte-binding that glycophorin B is a receptor for the P. falciparum protein EBL-1, a member of the Duffy-binding-like erythrocyte-binding protein (DBL-EBP) receptor family. The erythrocyte-binding domain, region 2 of EBL-1, expressed on CHO-K1 cells, bound glycophorin B(+) but not glycophorin B-null erythrocytes. In addition, glycophorin B(+) but not glycophorin B-null erythrocytes adsorbed native EBL-1 from the P. falciparum culture supernatants. Interestingly, the Efe pygmies of the Ituri forest in the Democratic Republic of the Congo have the highest gene frequency of glycophorin B-null in the world, raising the possibility that the DBL-EBP family may have expanded in response to the high frequency of glycophorin B-null in the population."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0900878106"xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0900878106"xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Jiang L."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Jiang L."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Hartl D.L."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Hartl D.L."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Miller L.H."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Miller L.H."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Kabat J."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Kabat J."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Mendoza L.H."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Mendoza L.H."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Tracy E."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Tracy E."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Mayer D.C."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Mayer D.C."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Cofie J."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/author | "Cofie J."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/19279206 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |