RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/19285002http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19285002http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19285002http://www.w3.org/2000/01/rdf-schema#comment"The novel protein modification, O-linked N-acetylglucosamine (O-GlcNAc), plays an important role in various aspects of cell regulation. Although most of nuclear transcription regulatory factors are modified by O-GlcNAc, O-GlcNAc effects on transcription remain largely undefined yet. In this study, we show that O-GlcNAc inhibits a physical interaction between Sp1 and Elf-1 transcription factors, and negatively regulates transcription of placenta and embryonic expression oncofetal protein gene (Pem). These findings suggest that O-GlcNAc inhibits Sp1-mediated gene transcription possibly by interrupting Sp1 interaction with its cooperative factor."xsd:string
http://purl.uniprot.org/citations/19285002http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2009.01.121"xsd:string
http://purl.uniprot.org/citations/19285002http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2009.01.121"xsd:string
http://purl.uniprot.org/citations/19285002http://purl.uniprot.org/core/author"Lim K."xsd:string
http://purl.uniprot.org/citations/19285002http://purl.uniprot.org/core/author"Lim K."xsd:string
http://purl.uniprot.org/citations/19285002http://purl.uniprot.org/core/author"Chang H.I."xsd:string
http://purl.uniprot.org/citations/19285002http://purl.uniprot.org/core/author"Chang H.I."xsd:string
http://purl.uniprot.org/citations/19285002http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19285002http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19285002http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/19285002http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/19285002http://purl.uniprot.org/core/pages"569-574"xsd:string
http://purl.uniprot.org/citations/19285002http://purl.uniprot.org/core/pages"569-574"xsd:string
http://purl.uniprot.org/citations/19285002http://purl.uniprot.org/core/title"O-GlcNAc inhibits interaction between Sp1 and Elf-1 transcription factors."xsd:string
http://purl.uniprot.org/citations/19285002http://purl.uniprot.org/core/title"O-GlcNAc inhibits interaction between Sp1 and Elf-1 transcription factors."xsd:string
http://purl.uniprot.org/citations/19285002http://purl.uniprot.org/core/volume"380"xsd:string
http://purl.uniprot.org/citations/19285002http://purl.uniprot.org/core/volume"380"xsd:string
http://purl.uniprot.org/citations/19285002http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19285002
http://purl.uniprot.org/citations/19285002http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19285002
http://purl.uniprot.org/citations/19285002http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19285002
http://purl.uniprot.org/citations/19285002http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19285002
http://purl.uniprot.org/uniprot/P08047http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/19285002
http://purl.uniprot.org/uniprot/P08047#attribution-B7150C4D652274486AB0E163D5110408http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/19285002