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http://purl.uniprot.org/citations/19286559http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19286559http://www.w3.org/2000/01/rdf-schema#comment"Most of the immunoglobulin A (IgA) in the gut is generated by B cells in the germinal centers of Peyer's patches through a process that requires the presence of CD4+ follicular B helper T(TFH) cells. The nature of these T(FH) cells in Peyer's patches has been elusive. Here, we demonstrate that suppressive Foxp3+CD4+ T cells can differentiate into TFH cells in mouse Peyer's patches. The conversion of Foxp3+ T cells into TFH cells requires the loss of Foxp3 expression and subsequent interaction with B cells. Thus, environmental cues present in gut Peyer's patches promote the selective differentiation of distinct helper T cell subsets, such as TFH cells."xsd:string
http://purl.uniprot.org/citations/19286559http://purl.org/dc/terms/identifier"doi:10.1126/science.1169152"xsd:string
http://purl.uniprot.org/citations/19286559http://purl.uniprot.org/core/author"Suzuki K."xsd:string
http://purl.uniprot.org/citations/19286559http://purl.uniprot.org/core/author"Honjo T."xsd:string
http://purl.uniprot.org/citations/19286559http://purl.uniprot.org/core/author"Tsuji M."xsd:string
http://purl.uniprot.org/citations/19286559http://purl.uniprot.org/core/author"Komatsu N."xsd:string
http://purl.uniprot.org/citations/19286559http://purl.uniprot.org/core/author"Kawamoto S."xsd:string
http://purl.uniprot.org/citations/19286559http://purl.uniprot.org/core/author"Hori S."xsd:string
http://purl.uniprot.org/citations/19286559http://purl.uniprot.org/core/author"Kanagawa O."xsd:string
http://purl.uniprot.org/citations/19286559http://purl.uniprot.org/core/author"Fagarasan S."xsd:string
http://purl.uniprot.org/citations/19286559http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19286559http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/19286559http://purl.uniprot.org/core/pages"1488-1492"xsd:string
http://purl.uniprot.org/citations/19286559http://purl.uniprot.org/core/title"Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches."xsd:string
http://purl.uniprot.org/citations/19286559http://purl.uniprot.org/core/volume"323"xsd:string
http://purl.uniprot.org/citations/19286559http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19286559
http://purl.uniprot.org/citations/19286559http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19286559
http://purl.uniprot.org/uniprot/#_A0A0B4J1L1-mappedCitation-19286559http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19286559
http://purl.uniprot.org/uniprot/#_A0A0G2JGZ6-mappedCitation-19286559http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19286559
http://purl.uniprot.org/uniprot/#_A0A0G2YDK5-mappedCitation-19286559http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19286559
http://purl.uniprot.org/uniprot/#_A0A0G2YJ29-mappedCitation-19286559http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19286559
http://purl.uniprot.org/uniprot/#_A0A0R4J096-mappedCitation-19286559http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19286559
http://purl.uniprot.org/uniprot/#_A0A3Q4EC35-mappedCitation-19286559http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19286559
http://purl.uniprot.org/uniprot/#_A0A3Q4EC46-mappedCitation-19286559http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19286559