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http://purl.uniprot.org/citations/19300485http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19300485http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19300485http://www.w3.org/2000/01/rdf-schema#comment"A common yet poorly understood evolutionary transition among flowering plants is a switch from outbreeding to an inbreeding mode of mating. The model plant Arabidopsis thaliana evolved to an inbreeding state through the loss of self-incompatibility, a pollen-rejection system in which pollen recognition by the stigma is determined by tightly linked and co-evolving alleles of the S-locus receptor kinase (SRK) and its S-locus cysteine-rich ligand (SCR). Transformation of A. thaliana, with a functional AlSRKb-SCRb gene pair from its outcrossing relative A. lyrata, demonstrated that A. thaliana accessions harbor different sets of cryptic self-fertility-promoting mutations, not only in S-locus genes, but also in other loci required for self-incompatibility. However, it is still not known how many times and in what manner the switch to self-fertility occurred in the A. thaliana lineage. Here, we report on our identification of four accessions that are reverted to full self-incompatibility by transformation with AlSRKb-SCRb, bringing to five the number of accessions in which self-fertility is due to, and was likely caused by, S-locus inactivation. Analysis of S-haplotype organization reveals that inter-haplotypic recombination events, rearrangements, and deletions have restructured the S locus and its genes in these accessions. We also perform a Quantitative Trait Loci (QTL) analysis to identify modifier loci associated with self-fertility in the Col-0 reference accession, which cannot be reverted to full self-incompatibility. Our results indicate that the transition to inbreeding occurred by at least two, and possibly more, independent S-locus mutations, and identify a novel unstable modifier locus that contributes to self-fertility in Col-0."xsd:string
http://purl.uniprot.org/citations/19300485http://purl.org/dc/terms/identifier"doi:10.1371/journal.pgen.1000426"xsd:string
http://purl.uniprot.org/citations/19300485http://purl.org/dc/terms/identifier"doi:10.1371/journal.pgen.1000426"xsd:string
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/author"Nasrallah M.E."xsd:string
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/author"Nasrallah M.E."xsd:string
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/author"Nasrallah J.B."xsd:string
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/author"Nasrallah J.B."xsd:string
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/author"Boggs N.A."xsd:string
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/author"Boggs N.A."xsd:string
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/name"PLoS Genet."xsd:string
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/name"PLoS Genet."xsd:string
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/pages"E1000426"xsd:string
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/pages"E1000426"xsd:string
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/title"Independent S-locus mutations caused self-fertility in Arabidopsis thaliana."xsd:string
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/title"Independent S-locus mutations caused self-fertility in Arabidopsis thaliana."xsd:string
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/volume"5"xsd:string
http://purl.uniprot.org/citations/19300485http://purl.uniprot.org/core/volume"5"xsd:string
http://purl.uniprot.org/citations/19300485http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19300485
http://purl.uniprot.org/citations/19300485http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19300485
http://purl.uniprot.org/citations/19300485http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19300485
http://purl.uniprot.org/citations/19300485http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19300485