| http://purl.uniprot.org/citations/19301403 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19301403 | http://www.w3.org/2000/01/rdf-schema#comment | "Leucine-rich repeat (LRR) -containing G protein coupled receptor (LGR) family members are characterized by the presence of a seven-transmembrane domain and LRR motifs. We describe a new function for Lgr4 in the development of the gall bladder and cystic duct and in the epithelium-mesenchyme interaction. Lgr4 expression was observed in the gall bladder epithelium when the gall bladder primordium elongated ventrally. Although Lgr4 hypomorphic mutant (Lgr4(Gt/Gt)) embryos developed a normal gall bladder bud at embryonic day (E) 10.25, no further elongation was observed at later stages. At E12.5, the mesenchyme surrounding the gall bladder had completely disappeared in Lgr4(Gt/Gt) embryos, while the gall bladder remained unelongated. Neighboring tissues such as liver and pancreas were unaffected, as revealed by expression of marker genes. This is the first report of a mutant mouse that lacks a gall bladder and cystic duct without affecting the other tissues that derive from the same hepatic diverticulum."xsd:string |
| http://purl.uniprot.org/citations/19301403 | http://purl.org/dc/terms/identifier | "doi:10.1002/dvdy.21900"xsd:string |
| http://purl.uniprot.org/citations/19301403 | http://purl.uniprot.org/core/author | "Araki K."xsd:string |
| http://purl.uniprot.org/citations/19301403 | http://purl.uniprot.org/core/author | "Yamashita R."xsd:string |
| http://purl.uniprot.org/citations/19301403 | http://purl.uniprot.org/core/author | "Nakahara M."xsd:string |
| http://purl.uniprot.org/citations/19301403 | http://purl.uniprot.org/core/author | "Hoshii T."xsd:string |
| http://purl.uniprot.org/citations/19301403 | http://purl.uniprot.org/core/author | "Yamamura K."xsd:string |
| http://purl.uniprot.org/citations/19301403 | http://purl.uniprot.org/core/author | "Yokouchi Y."xsd:string |
| http://purl.uniprot.org/citations/19301403 | http://purl.uniprot.org/core/author | "Kawazu H."xsd:string |
| http://purl.uniprot.org/citations/19301403 | http://purl.uniprot.org/core/author | "Sakumoto M."xsd:string |
| http://purl.uniprot.org/citations/19301403 | http://purl.uniprot.org/core/author | "Takegawa Y."xsd:string |
| http://purl.uniprot.org/citations/19301403 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19301403 | http://purl.uniprot.org/core/name | "Dev Dyn"xsd:string |
| http://purl.uniprot.org/citations/19301403 | http://purl.uniprot.org/core/pages | "993-1000"xsd:string |
| http://purl.uniprot.org/citations/19301403 | http://purl.uniprot.org/core/title | "Defective development of the gall bladder and cystic duct in Lgr4- hypomorphic mice."xsd:string |
| http://purl.uniprot.org/citations/19301403 | http://purl.uniprot.org/core/volume | "238"xsd:string |
| http://purl.uniprot.org/citations/19301403 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19301403 |
| http://purl.uniprot.org/citations/19301403 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19301403 |
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| http://purl.uniprot.org/uniprot/#_P52946-mappedCitation-19301403 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19301403 |
| http://purl.uniprot.org/uniprot/#_A2ARI4-mappedCitation-19301403 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19301403 |
| http://purl.uniprot.org/uniprot/#_P02772-mappedCitation-19301403 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19301403 |
| http://purl.uniprot.org/uniprot/#_K7R066-mappedCitation-19301403 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19301403 |
| http://purl.uniprot.org/uniprot/#_P07724-mappedCitation-19301403 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19301403 |