http://purl.uniprot.org/citations/19331813 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19331813 | http://www.w3.org/2000/01/rdf-schema#comment | "Mutations of PKD1 cause autosomal dominant polycystic kidney disease (ADPKD), a syndrome characterized by kidney cysts and progressive renal failure. Polycystin-1, the protein encoded by PKD1, is a large integral membrane protein with a short carboxy-terminal cytoplasmic domain that appears to initiate multiple cellular programs. We report now that this polycystin-1 domain contains a novel motif responsible for rearrangements of intermediate filaments, microtubules and the endoplasmic reticulum (ER). This motif reveals homology to CLIMP-63, a microtubule-binding protein that rearranges the ER. Our findings suggest that polycystin-1 influences the shape and localization of both the microtubular network and the ER."xsd:string |
http://purl.uniprot.org/citations/19331813 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.yexcr.2009.01.027"xsd:string |
http://purl.uniprot.org/citations/19331813 | http://purl.uniprot.org/core/author | "Gao H."xsd:string |
http://purl.uniprot.org/citations/19331813 | http://purl.uniprot.org/core/author | "Walz G."xsd:string |
http://purl.uniprot.org/citations/19331813 | http://purl.uniprot.org/core/author | "Nickel C."xsd:string |
http://purl.uniprot.org/citations/19331813 | http://purl.uniprot.org/core/author | "Gerke P."xsd:string |
http://purl.uniprot.org/citations/19331813 | http://purl.uniprot.org/core/author | "Nitschke R."xsd:string |
http://purl.uniprot.org/citations/19331813 | http://purl.uniprot.org/core/author | "Kramer-Zucker A.G."xsd:string |
http://purl.uniprot.org/citations/19331813 | http://purl.uniprot.org/core/author | "Putz M."xsd:string |
http://purl.uniprot.org/citations/19331813 | http://purl.uniprot.org/core/author | "Imgrund M."xsd:string |
http://purl.uniprot.org/citations/19331813 | http://purl.uniprot.org/core/author | "Sellin L.K."xsd:string |
http://purl.uniprot.org/citations/19331813 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19331813 | http://purl.uniprot.org/core/name | "Exp Cell Res"xsd:string |
http://purl.uniprot.org/citations/19331813 | http://purl.uniprot.org/core/pages | "1157-1170"xsd:string |
http://purl.uniprot.org/citations/19331813 | http://purl.uniprot.org/core/title | "A short carboxy-terminal domain of polycystin-1 reorganizes the microtubular network and the endoplasmic reticulum."xsd:string |
http://purl.uniprot.org/citations/19331813 | http://purl.uniprot.org/core/volume | "315"xsd:string |
http://purl.uniprot.org/citations/19331813 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19331813 |
http://purl.uniprot.org/citations/19331813 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19331813 |
http://purl.uniprot.org/uniprot/#_A0A097HUC6-mappedCitation-19331813 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19331813 |
http://purl.uniprot.org/uniprot/#_A0A867GBE4-mappedCitation-19331813 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19331813 |
http://purl.uniprot.org/uniprot/#_C1JFL5-mappedCitation-19331813 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19331813 |
http://purl.uniprot.org/uniprot/#_C1JFL6-mappedCitation-19331813 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19331813 |
http://purl.uniprot.org/uniprot/#_C1JFL7-mappedCitation-19331813 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19331813 |
http://purl.uniprot.org/uniprot/#_Q59EY6-mappedCitation-19331813 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19331813 |