| http://purl.uniprot.org/citations/19358823 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19358823 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19358823 | http://www.w3.org/2000/01/rdf-schema#comment | "Terf/TRIM17 is a member of the TRIM family of proteins, which is characterized by the RING finger, B-box, and coiled-coil domains. In the present study, we found that terf interacts with TRIM44. Terf underwent ubiquitination in vitro in the presence of the E2 enzyme UbcH6; this suggests that terf exhibits E3 ubiquitin ligase activity. It was also found that terf was conjugated with polyubiquitin chains and stabilized by the proteasome inhibitor in mammalian cells; this suggested that terf rendered itself susceptible to proteasomal degradation through polyubiquitination. We also found that TRIM44 inhibited ubiquitination of terf, and thus stabilized the protein. The N-terminal region of TRIM44 contains a zinc-finger domain found in ubiquitin hydrolases (ZF UBP) and ubiquitin specific proteases (USPs). Thus, we proposed that TRIM44 may function as a new class of the "USP-like-TRIM" which regulates the activity of associated TRIM proteins."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2009.04.010"xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2009.04.010"xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Ishida Y."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Ishida Y."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Iwayanagi T."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Iwayanagi T."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Ikeda K."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Ikeda K."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Inoue S."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Inoue S."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Takeda S."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Takeda S."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Okada A."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Okada A."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Otomo J."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Otomo J."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Urano T."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Urano T."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Usui T."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Usui T."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Ouchi Y."xsd:string |
| http://purl.uniprot.org/citations/19358823 | http://purl.uniprot.org/core/author | "Ouchi Y."xsd:string |