http://purl.uniprot.org/citations/19362996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19362996 | http://www.w3.org/2000/01/rdf-schema#comment | "BackgroundA hypersensitivity reaction (HSR) is associated with abacavir (ABC), a nucleoside reverse transcriptase inhibitor. Genetic association of ABC HSR with the presence of HLA-B*5701 has been demonstrated in PREDICT-1 study, showing a prevalence of 5.6% in HIV-infected population. However the prevalence of this allele in HIV-infected patients in Spain has not been established yet.MethodThis is a cross-sectional epidemiological study that included 1,198 patients in 74 centers that serve the HIV-infected population of Spain. HLA-B*5701 was checked both in the hospital lab and one central lab, showing an overall prevalence of this allele of 6%.ResultsHLA-B*5701 was most prevalent in Caucasian population (6.5%). Concordance between the local and central lab was very high for positive and negative results (95.7% and 99.3%, respectively).ConclusionThese aspects define this test as a useful tool for the management of HIV-infected patients."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.org/dc/terms/identifier | "doi:10.1310/hct1001-048"xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Hernandez J."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Rodriguez R."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Martinez E."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Martin T."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Berenguer J."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Munoz A."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Gatell J.M."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Knobel H."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Ortega E."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Munoz J."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Ocampo A."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Flores J."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Guerrero F."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Cordero M."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Gutierrez F."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Lozano F."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Del Pozo M.A."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Riera M."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Rubio R."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Sola J."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Oteo J.A."xsd:string |
http://purl.uniprot.org/citations/19362996 | http://purl.uniprot.org/core/author | "Soriano V."xsd:string |