| http://purl.uniprot.org/citations/19368858 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19368858 | http://www.w3.org/2000/01/rdf-schema#comment | "Several studies have reported an association between the ApolipoproteinE-epsilon4 (APOE4) allele and depression among elders. However others have failed to find an association. Since APOE4 is a well recognized risk factor for Alzheimer dementia, cognitive status may represent an important confounder between APOE4 and depression. In this investigation, we examined the relationship between the ApolipoproteinE-epsilon4 allele and depression among elders accounting for cognitive status. Using a case-control design (n=1052), we investigated the association between ApolipoproteinE-epsilon4 and depression in Alzheimer disease patients (n=528) and in cognitively intact controls (n=524). We demonstrated an apparent association between the APOE4 allele and depression in the combined dataset (p=0.001) when not controlling for cognitive status. However, once stratified by the presence of Alzheimer disease, there was no association in either the Alzheimer group (p=0.290) or the cognitively intact controls (p=0.494). In this dataset there is no association between the ApolipoproteinE-epsilon4 allele and depression among those with Alzheimer disease or among cognitively intact elders. However there is a significant association between female gender and depression in the cognitively intact (p=0.003) but not among those with Alzheimer disease. Additionally, individuals with Alzheimer disease and depression had a significantly younger age of onset for their Alzheimer disease than those without depression (p=0.017)."xsd:string |
| http://purl.uniprot.org/citations/19368858 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.neulet.2009.03.007"xsd:string |
| http://purl.uniprot.org/citations/19368858 | http://purl.uniprot.org/core/author | "Haines J.L."xsd:string |
| http://purl.uniprot.org/citations/19368858 | http://purl.uniprot.org/core/author | "Pericak-Vance M.A."xsd:string |
| http://purl.uniprot.org/citations/19368858 | http://purl.uniprot.org/core/author | "Gilbert J.R."xsd:string |
| http://purl.uniprot.org/citations/19368858 | http://purl.uniprot.org/core/author | "Martin E.R."xsd:string |
| http://purl.uniprot.org/citations/19368858 | http://purl.uniprot.org/core/author | "Slifer M.A."xsd:string |
| http://purl.uniprot.org/citations/19368858 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19368858 | http://purl.uniprot.org/core/name | "Neurosci Lett"xsd:string |
| http://purl.uniprot.org/citations/19368858 | http://purl.uniprot.org/core/pages | "116-119"xsd:string |
| http://purl.uniprot.org/citations/19368858 | http://purl.uniprot.org/core/title | "Resolving the relationship between ApolipoproteinE and depression."xsd:string |
| http://purl.uniprot.org/citations/19368858 | http://purl.uniprot.org/core/volume | "455"xsd:string |
| http://purl.uniprot.org/citations/19368858 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19368858 |
| http://purl.uniprot.org/citations/19368858 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19368858 |
| http://purl.uniprot.org/uniprot/#_A0A0S2Z3B1-mappedCitation-19368858 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19368858 |
| http://purl.uniprot.org/uniprot/#_A0A0S2Z3V0-mappedCitation-19368858 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19368858 |
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| http://purl.uniprot.org/uniprot/#_A0A346DBY2-mappedCitation-19368858 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19368858 |
| http://purl.uniprot.org/uniprot/#_D9ZB55-mappedCitation-19368858 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19368858 |
| http://purl.uniprot.org/uniprot/#_J9ZVQ3-mappedCitation-19368858 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19368858 |
| http://purl.uniprot.org/uniprot/#_P02649-mappedCitation-19368858 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19368858 |
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| http://purl.uniprot.org/uniprot/#_Q6LBZ1-mappedCitation-19368858 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19368858 |