| http://purl.uniprot.org/citations/19371377 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19371377 | http://www.w3.org/2000/01/rdf-schema#comment | "[PIN(+)] is a prion form of Rnq1 in Saccharomyces cerevisiae and is necessary for the de novo induction of a second prion, [PSI(+)]. We previously isolated a truncated form of Rnq1, named Rnq1Delta100, as a [PSI(+)]-eliminating factor in S. cerevisiae. Rnq1Delta100 deletes the N-terminal non-prion domain of Rnq1, and eliminates [PSI(+)] in [PIN(+)] yeast. Here we found that [PIN(+)] is transmissible to Rnq1Delta100 in the absence of full-length Rnq1, forming a novel prion variant [RNQ1Delta100(+)]. [RNQ1Delta100(+)] has similar [PIN(+)] properties as it stimulates the de novo induction of [PSI(+)] and is eliminated by the null hsp104Delta mutation, but not by Hsp104 overproduction. In contrast, [RNQ1Delta100(+)] inherits the inhibitory activity and hampers the maintenance of [PSI(+)] though less efficiently than [PIN(+)] made of Rnq1-Rnq1Delta100 co-aggregates. Interestingly, [RNQ1Delta100(+)] prion was eliminated by de novo [PSI(+)] induction. Thus, the [RNQ1Delta100(+)] prion demonstrates selfish activity to eliminate a heterologous prion in S. cerevisiae, showing the first instance of a selfish prion variant in living organisms."xsd:string |
| http://purl.uniprot.org/citations/19371377 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1365-2443.2009.01297.x"xsd:string |
| http://purl.uniprot.org/citations/19371377 | http://purl.uniprot.org/core/author | "Nakamura Y."xsd:string |
| http://purl.uniprot.org/citations/19371377 | http://purl.uniprot.org/core/author | "Kurahashi H."xsd:string |
| http://purl.uniprot.org/citations/19371377 | http://purl.uniprot.org/core/author | "Shibata S."xsd:string |
| http://purl.uniprot.org/citations/19371377 | http://purl.uniprot.org/core/author | "Ishiwata M."xsd:string |
| http://purl.uniprot.org/citations/19371377 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19371377 | http://purl.uniprot.org/core/name | "Genes Cells"xsd:string |
| http://purl.uniprot.org/citations/19371377 | http://purl.uniprot.org/core/pages | "659-668"xsd:string |
| http://purl.uniprot.org/citations/19371377 | http://purl.uniprot.org/core/title | "Selfish prion of Rnq1 mutant in yeast."xsd:string |
| http://purl.uniprot.org/citations/19371377 | http://purl.uniprot.org/core/volume | "14"xsd:string |
| http://purl.uniprot.org/citations/19371377 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19371377 |
| http://purl.uniprot.org/citations/19371377 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19371377 |
| http://purl.uniprot.org/uniprot/#_K4I0B6-mappedCitation-19371377 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19371377 |
| http://purl.uniprot.org/uniprot/#_P25367-mappedCitation-19371377 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19371377 |
| http://purl.uniprot.org/uniprot/P25367 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19371377 |
| http://purl.uniprot.org/uniprot/K4I0B6 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19371377 |