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http://purl.uniprot.org/citations/19392836http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19392836http://www.w3.org/2000/01/rdf-schema#comment"We have shown earlier the association of human leucocyte antigen (HLA)-A11 with resistance and HLA-B40 and -DR2 with susceptibility to HIV and HIV-TB. In the present study, we have attempted to find out the HLA-DR2 subtypes and the possible HLA-A/-B/-DRB1 haplotype combinations that are associated with susceptibility or resistance to HIV and HIV with pulmonary tuberculosis (HIV+PTB+). HLA-DR2 subtyping was carried out by polymerase chain reaction-based sequence-specific oligonucleotide probe method. Overrepresentation of HLA-DRB1*1501 in HIV-positive PTB-negative (HIV+PTB-) patients (P = 0.004, P(c) = 0.06) and -DRB1*1502 in HIV-positive PTB-positive (HIV+PTB+) patients (P = 0.019) was observed as compared to healthy controls. Haplotype analysis revealed an increased frequency of HLA-A2-DRB1*1501 haplotype in HIV+PTB-patients (P = 0.008) and HLA-A2-DRB1*1502 among HIV+PTB+ patients (P = 0.01) compared to healthy controls. The haplotypes B40-DRB1*1501 and B40-DRB1*04 were found to be moderately increased in HIV+PTB(-) and HIV+PTB+ patients (P < 0.05). The study suggests that HLA-A2-DRB1*1501 haplotype may be associated with HIV infection while HLA-A2-DRB1*1502 haplotype might be associated with susceptibility to PTB in HIV patients. Moreover, HLA-B40-DRB1*1501 and HLA-B40-DRB1*04 haplotypes may be associated with susceptibility to HIV infection and to PTB in HIV patients."xsd:string
http://purl.uniprot.org/citations/19392836http://purl.org/dc/terms/identifier"doi:10.1111/j.1744-313x.2009.00835.x"xsd:string
http://purl.uniprot.org/citations/19392836http://purl.uniprot.org/core/author"Swaminathan S."xsd:string
http://purl.uniprot.org/citations/19392836http://purl.uniprot.org/core/author"Narayanan P.R."xsd:string
http://purl.uniprot.org/citations/19392836http://purl.uniprot.org/core/author"Raghavan S."xsd:string
http://purl.uniprot.org/citations/19392836http://purl.uniprot.org/core/author"Selvaraj P."xsd:string
http://purl.uniprot.org/citations/19392836http://purl.uniprot.org/core/author"Alagarasu K."xsd:string
http://purl.uniprot.org/citations/19392836http://purl.uniprot.org/core/author"Narendran G."xsd:string
http://purl.uniprot.org/citations/19392836http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19392836http://purl.uniprot.org/core/name"Int J Immunogenet"xsd:string
http://purl.uniprot.org/citations/19392836http://purl.uniprot.org/core/pages"129-133"xsd:string
http://purl.uniprot.org/citations/19392836http://purl.uniprot.org/core/title"Haplotype analysis of HLA-A, -B antigens and -DRB1 alleles in south Indian HIV-1-infected patients with and without pulmonary tuberculosis."xsd:string
http://purl.uniprot.org/citations/19392836http://purl.uniprot.org/core/volume"36"xsd:string
http://purl.uniprot.org/citations/19392836http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19392836
http://purl.uniprot.org/citations/19392836http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19392836
http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-19392836http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19392836
http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-19392836http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19392836
http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-19392836http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19392836
http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-19392836http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19392836
http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-19392836http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19392836
http://purl.uniprot.org/uniprot/#_A0A0A7C552-mappedCitation-19392836http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19392836
http://purl.uniprot.org/uniprot/#_A0A0E3DC98-mappedCitation-19392836http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19392836
http://purl.uniprot.org/uniprot/#_A0A0E3DCA0-mappedCitation-19392836http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19392836
http://purl.uniprot.org/uniprot/#_A0A0E3DCA1-mappedCitation-19392836http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19392836