| http://purl.uniprot.org/citations/19403456 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19403456 | http://www.w3.org/2000/01/rdf-schema#comment | "Functional polymorphism in the genes encoding alcohol dehydrogenase (ADH) 1B and aldehyde dehydrogenase (ALDH) 2 are considered most important among several genetic determinants of alcohol dependence, a complex disorder. There is no report on the widely studied Arg47His and Glu487Lys polymorphisms from Indian alcohol-dependent populations. In this paper, we report, for the first time, allelic and genotypic frequencies of Arg47His and Glu487Lys single nucleotide polymorphisms (SNPs) in North Indian alcohol-dependent subjects. A total of 174 alcohol-dependent males, recruited using DSM IV criteria (American Psychiatric Association, 1994), were genotyped using the polymerase chain reaction-restriction fragment length polymorphism method. The results obtained from genetic analysis were correlated with clinical parameters using Student's t-test or Mann Whitney's U test. The highlight of the study findings was the uniquely high frequency of the ALDH2*2/*2 genotype (among alcohol-dependent subjects) being a risk-conferring factor for alcohol dependence."xsd:string |
| http://purl.uniprot.org/citations/19403456 | http://purl.org/dc/terms/identifier | "doi:10.1186/1479-7364-3-3-213"xsd:string |
| http://purl.uniprot.org/citations/19403456 | http://purl.uniprot.org/core/author | "Prasad P."xsd:string |
| http://purl.uniprot.org/citations/19403456 | http://purl.uniprot.org/core/author | "Kapur S."xsd:string |
| http://purl.uniprot.org/citations/19403456 | http://purl.uniprot.org/core/author | "Vaswani M."xsd:string |
| http://purl.uniprot.org/citations/19403456 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19403456 | http://purl.uniprot.org/core/name | "Hum Genomics"xsd:string |
| http://purl.uniprot.org/citations/19403456 | http://purl.uniprot.org/core/pages | "213-220"xsd:string |
| http://purl.uniprot.org/citations/19403456 | http://purl.uniprot.org/core/title | "Association of ADH1B and ALDH2 gene polymorphisms with alcohol dependence: a pilot study from India."xsd:string |
| http://purl.uniprot.org/citations/19403456 | http://purl.uniprot.org/core/volume | "3"xsd:string |
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