| http://purl.uniprot.org/citations/19414773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19414773 | http://www.w3.org/2000/01/rdf-schema#comment | "CD62L (L-selectin) is a key regulator of T cell trafficking, and its surface expression on activated T cells is modulated to control T cell access to lymph nodes after acute infections. In memory T cells, CD62L is the most frequently used marker to define central memory T cells, a population that provides enhanced protection against most, but not all, pathogens. Early access of CD62L(pos) effector T cells to lymph nodes has been proposed to result in preferential central memory T cell differentiation, but direct proof for the involvement of lymph node homing in memory T cell differentiation is lacking. In this study, we show that central memory lineage commitment in CD8 T cells is unaltered by enhanced entry into lymph nodes as a result of constitutive CD62L expression, and that equal numbers of effector and central memory CD8 T cells develop in the absence of CD62L-mediated lymph node trafficking. Our results suggest that CD62L is not a deterministic marker of central memory T cell differentiation, thus providing new insight into the process of memory CD8 T cell generation."xsd:string |
| http://purl.uniprot.org/citations/19414773 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.0803315"xsd:string |
| http://purl.uniprot.org/citations/19414773 | http://purl.uniprot.org/core/author | "Zhao L."xsd:string |
| http://purl.uniprot.org/citations/19414773 | http://purl.uniprot.org/core/author | "Harty J.T."xsd:string |
| http://purl.uniprot.org/citations/19414773 | http://purl.uniprot.org/core/author | "Badovinac V.P."xsd:string |
| http://purl.uniprot.org/citations/19414773 | http://purl.uniprot.org/core/author | "Dailey M.O."xsd:string |
| http://purl.uniprot.org/citations/19414773 | http://purl.uniprot.org/core/author | "Wirth T.C."xsd:string |
| http://purl.uniprot.org/citations/19414773 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19414773 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/19414773 | http://purl.uniprot.org/core/pages | "6195-6206"xsd:string |
| http://purl.uniprot.org/citations/19414773 | http://purl.uniprot.org/core/title | "Differentiation of central memory CD8 T cells is independent of CD62L-mediated trafficking to lymph nodes."xsd:string |
| http://purl.uniprot.org/citations/19414773 | http://purl.uniprot.org/core/volume | "182"xsd:string |
| http://purl.uniprot.org/citations/19414773 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19414773 |
| http://purl.uniprot.org/citations/19414773 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19414773 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YW25-mappedCitation-19414773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19414773 |
| http://purl.uniprot.org/uniprot/#_B1B506-mappedCitation-19414773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19414773 |
| http://purl.uniprot.org/uniprot/#_B1B507-mappedCitation-19414773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19414773 |
| http://purl.uniprot.org/uniprot/#_Q3UV83-mappedCitation-19414773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19414773 |
| http://purl.uniprot.org/uniprot/#_P09225-mappedCitation-19414773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19414773 |
| http://purl.uniprot.org/uniprot/#_P18337-mappedCitation-19414773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19414773 |
| http://purl.uniprot.org/uniprot/#_Q3TCF3-mappedCitation-19414773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19414773 |
| http://purl.uniprot.org/uniprot/#_Q3TA36-mappedCitation-19414773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19414773 |
| http://purl.uniprot.org/uniprot/#_Q3TR50-mappedCitation-19414773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19414773 |
| http://purl.uniprot.org/uniprot/#_Q3TSW6-mappedCitation-19414773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19414773 |