| http://purl.uniprot.org/citations/19427866 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19427866 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19427866 | http://www.w3.org/2000/01/rdf-schema#comment | "Nbr1, a ubiquitous kinase scaffold protein, contains a PB1, and a ubiquitin-associated (UBA) domain. We show here that the nbr1 UBA domain binds to lysine-48 and -63 linked polyubiquitin-B chains. Nbr1 also binds to the autophagic effector protein LC3-A via a novel binding site. Ubiquitin-binding, but not PB1-mediated p62/SQSTM1 interaction, is required to target nbr1 to LC3 and polyubiquitin-positive bodies. Nbr1 binds additionally to proteins implicated in ubiquitin-mediated protein turnover and vesicle trafficking: ubiquitin-specific peptidases USP8, and the endosomal transport regulator p14/Robld3. Nbr1 thus contributes to specific steps in protein turnover regulation disrupted in several hereditary human diseases."xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2009.04.049"xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2009.04.049"xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/author | "Gautel M."xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/author | "Gautel M."xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/author | "Solomon E."xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/author | "Solomon E."xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/author | "Whitehouse C."xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/author | "Whitehouse C."xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/author | "Waters S."xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/author | "Waters S."xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/author | "Marchbank K."xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/author | "Marchbank K."xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/pages | "1846-1852"xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/pages | "1846-1852"xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/title | "Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover."xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/title | "Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover."xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/volume | "583"xsd:string |
| http://purl.uniprot.org/citations/19427866 | http://purl.uniprot.org/core/volume | "583"xsd:string |