| http://purl.uniprot.org/citations/19430480 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19430480 | http://www.w3.org/2000/01/rdf-schema#comment | "Type 1 diabetes (T1D) is a common autoimmune disorder that arises from the action of multiple genetic and environmental risk factors. We report the findings of a genome-wide association study of T1D, combined in a meta-analysis with two previously published studies. The total sample set included 7,514 cases and 9,045 reference samples. Forty-one distinct genomic locations provided evidence for association with T1D in the meta-analysis (P < 10(-6)). After excluding previously reported associations, we further tested 27 regions in an independent set of 4,267 cases, 4,463 controls and 2,319 affected sib-pair (ASP) families. Of these, 18 regions were replicated (P < 0.01; overall P < 5 × 10(-8)) and 4 additional regions provided nominal evidence of replication (P < 0.05). The many new candidate genes suggested by these results include IL10, IL19, IL20, GLIS3, CD69 and IL27."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng.381"xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Brown M."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Adlem E."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Altshuler D."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Carlson J."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Cooper J."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Becker D."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Bhatia S."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Field L."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Deloukas P."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Devlin B."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "He C."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Ghosh S."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Jones T."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Han X."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Li D."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Lu L."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Kim S."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Long A."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Howell S."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Goodman N."xsd:string |
| http://purl.uniprot.org/citations/19430480 | http://purl.uniprot.org/core/author | "Lee Y.J."xsd:string |