| http://purl.uniprot.org/citations/19433630 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19433630 | http://www.w3.org/2000/01/rdf-schema#comment | "To gain new mechanistic insight into ER homeostasis and the biogenesis of secretory proteins, we screened a genomewide collection of yeast mutants for defective intracellular retention of the ER chaperone, Kar2p. We identified 87 Kar2p-secreting strains, including a number of known components in secretory protein modification and sorting. Further characterization of the 73 nonessential Kar2p retention mutants revealed roles for a number of novel gene products in protein glycosylation, GPI-anchor attachment, ER quality control, and retrieval of escaped ER residents. A subset of these mutants, required for ER retrieval, included the GET complex and two novel proteins that likely function similarly in membrane insertion of tail-anchored proteins. Finally, the variant histone, Htz1p, and its acetylation state seem to play an important role in maintaining ER retrieval pathways, suggesting a surprising link between chromatin remodeling and ER homeostasis."xsd:string |
| http://purl.uniprot.org/citations/19433630 | http://purl.org/dc/terms/identifier | "doi:10.1534/genetics.109.101105"xsd:string |
| http://purl.uniprot.org/citations/19433630 | http://purl.uniprot.org/core/author | "Lee M.C."xsd:string |
| http://purl.uniprot.org/citations/19433630 | http://purl.uniprot.org/core/author | "Singh I."xsd:string |
| http://purl.uniprot.org/citations/19433630 | http://purl.uniprot.org/core/author | "Barry J."xsd:string |
| http://purl.uniprot.org/citations/19433630 | http://purl.uniprot.org/core/author | "Pagant S."xsd:string |
| http://purl.uniprot.org/citations/19433630 | http://purl.uniprot.org/core/author | "Miller E.A."xsd:string |
| http://purl.uniprot.org/citations/19433630 | http://purl.uniprot.org/core/author | "Copic A."xsd:string |
| http://purl.uniprot.org/citations/19433630 | http://purl.uniprot.org/core/author | "Dorrington M."xsd:string |
| http://purl.uniprot.org/citations/19433630 | http://purl.uniprot.org/core/author | "Hartman J.L."xsd:string |
| http://purl.uniprot.org/citations/19433630 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19433630 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/19433630 | http://purl.uniprot.org/core/pages | "757-769"xsd:string |
| http://purl.uniprot.org/citations/19433630 | http://purl.uniprot.org/core/title | "Genomewide analysis reveals novel pathways affecting endoplasmic reticulum homeostasis, protein modification and quality control."xsd:string |
| http://purl.uniprot.org/citations/19433630 | http://purl.uniprot.org/core/volume | "182"xsd:string |
| http://purl.uniprot.org/citations/19433630 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19433630 |
| http://purl.uniprot.org/citations/19433630 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19433630 |
| http://purl.uniprot.org/uniprot/Q12150#attribution-6DADCC4E74937197E45D8562118584C6 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19433630 |
| http://purl.uniprot.org/uniprot/P38264#attribution-6DADCC4E74937197E45D8562118584C6 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19433630 |
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| http://purl.uniprot.org/uniprot/#_A0A6A5Q818-mappedCitation-19433630 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19433630 |
| http://purl.uniprot.org/uniprot/#_P16474-mappedCitation-19433630 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19433630 |
| http://purl.uniprot.org/uniprot/#_P38178-mappedCitation-19433630 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19433630 |
| http://purl.uniprot.org/uniprot/#_P38179-mappedCitation-19433630 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19433630 |