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http://purl.uniprot.org/citations/19455600http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19455600http://www.w3.org/2000/01/rdf-schema#comment"In order to evaluate the contribution of 19 serotonin-related genes to the susceptibility to migraine in a Spanish population we performed a case-control association study of 122 single nucleotide polymorphisms (SNPs), selected according to genetic coverage parameters, in 528 migraine patients -308 with migraine without aura (MO) and 220 with migraine with aura (MA)- and 528 sex-matched migraine-free controls. The single-marker analysis identified nominal associations with the migraine phenotype or with the MO or MA subtypes. The multiple-marker analysis revealed risk haplotypes in three genes that remained significantly associated with migraine after correction by permutations. Two-marker risk haplotypes were identified in the HTR2B (rs16827801T-rs10194776G) and MAOA (rs3027400G-rs2072743C) genes conferring susceptibility to MO, and a four-marker haplotype in DDC was specific of MA (rs2329340A-rs11974297C-rs2044859T-rs11761683G). The present study supports the involvement of HTR2B and MAOA genes in the genetic predisposition to MO, while DDC might confer susceptibility to MA. These results suggest a differential involvement of serotonin-related genes in the genetic background of MO and MA."xsd:string
http://purl.uniprot.org/citations/19455600http://purl.org/dc/terms/identifier"doi:10.1002/ajmg.b.30972"xsd:string
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/author"Roig M."xsd:string
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/author"Blanco-Arias P."xsd:string
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/author"Sobrido M.J."xsd:string
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/author"Corominas R."xsd:string
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/author"Ribases M."xsd:string
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/author"Cormand B."xsd:string
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/author"Cuenca-Leon E."xsd:string
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/author"Macaya A."xsd:string
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/author"Narberhaus B."xsd:string
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/author"Leira R."xsd:string
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/author"Lopez-Gonzalez J."xsd:string
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/name"Am J Med Genet B Neuropsychiatr Genet"xsd:string
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/pages"177-184"xsd:string
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/title"Association study of the serotoninergic system in migraine in the Spanish population."xsd:string
http://purl.uniprot.org/citations/19455600http://purl.uniprot.org/core/volume"153B"xsd:string
http://purl.uniprot.org/citations/19455600http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19455600
http://purl.uniprot.org/citations/19455600http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19455600
http://purl.uniprot.org/uniprot/#_A0A087WV24-mappedCitation-19455600http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19455600
http://purl.uniprot.org/uniprot/#_A8K215-mappedCitation-19455600http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19455600
http://purl.uniprot.org/uniprot/#_A0A1W5KJW8-mappedCitation-19455600http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19455600
http://purl.uniprot.org/uniprot/#_A0A7L4XSC9-mappedCitation-19455600http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19455600