| http://purl.uniprot.org/citations/19463952 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19463952 | http://www.w3.org/2000/01/rdf-schema#comment | "Shal K+ (K(v)4) channels across species carry the major A-type K+ current present in neurons. Shal currents are activated by small EPSPs and modulate post-synaptic potentials, backpropagation of action potentials, and induction of LTP. Fast inactivation of Shal channels regulates the impact of this post-synaptic modulation. Here, we introduce SKIP3, as the first protein interactor of Drosophila Shal K+ channels. The SKIP gene encodes three isoforms with multiple protein-protein interaction domains. SKIP3 is nervous system specific and co-localizes with Shal channels in neuronal cell bodies, and in puncta along processes. Using a genetic deficiency of SKIP, we show that the proportion of neurons displaying a very fast inactivation, consistent with Shal channels exclusively in a "fast" gating mode, is increased in the absence of SKIP3. As a scaffold-like protein, SKIP3 is likely to lead to the identification of a novel regulatory complex that modulates Shal channel inactivation."xsd:string |
| http://purl.uniprot.org/citations/19463952 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.mcn.2009.05.003"xsd:string |
| http://purl.uniprot.org/citations/19463952 | http://purl.uniprot.org/core/author | "Diao F."xsd:string |
| http://purl.uniprot.org/citations/19463952 | http://purl.uniprot.org/core/author | "Tsunoda S."xsd:string |
| http://purl.uniprot.org/citations/19463952 | http://purl.uniprot.org/core/author | "Waro G."xsd:string |
| http://purl.uniprot.org/citations/19463952 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19463952 | http://purl.uniprot.org/core/name | "Mol Cell Neurosci"xsd:string |
| http://purl.uniprot.org/citations/19463952 | http://purl.uniprot.org/core/pages | "33-44"xsd:string |
| http://purl.uniprot.org/citations/19463952 | http://purl.uniprot.org/core/title | "Fast inactivation of Shal (K(v)4) K+ channels is regulated by the novel interactor SKIP3 in Drosophila neurons."xsd:string |
| http://purl.uniprot.org/citations/19463952 | http://purl.uniprot.org/core/volume | "42"xsd:string |
| http://purl.uniprot.org/citations/19463952 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19463952 |
| http://purl.uniprot.org/citations/19463952 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19463952 |
| http://purl.uniprot.org/uniprot/P17971#attribution-26907B5329D48921CFCD31A4C4B3CE06 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19463952 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KHM3-mappedCitation-19463952 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19463952 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KHV7-mappedCitation-19463952 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19463952 |
| http://purl.uniprot.org/uniprot/#_A0A0S0X7Z4-mappedCitation-19463952 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19463952 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KH49-mappedCitation-19463952 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19463952 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K6C1-mappedCitation-19463952 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19463952 |
| http://purl.uniprot.org/uniprot/#_A0A0B4JCZ4-mappedCitation-19463952 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19463952 |
| http://purl.uniprot.org/uniprot/#_A0A126GV04-mappedCitation-19463952 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19463952 |
| http://purl.uniprot.org/uniprot/#_A8JNI9-mappedCitation-19463952 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19463952 |
| http://purl.uniprot.org/uniprot/#_E1JJQ5-mappedCitation-19463952 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19463952 |
| http://purl.uniprot.org/uniprot/#_M9NFJ6-mappedCitation-19463952 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19463952 |
| http://purl.uniprot.org/uniprot/#_M9NFP7-mappedCitation-19463952 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19463952 |