| http://purl.uniprot.org/citations/19477154 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19477154 | http://www.w3.org/2000/01/rdf-schema#comment | "A key feature of escape responses is the fast translation of sensory information into a coordinated motor output. In C. elegans, anterior touch initiates a backward escape response in which lateral head movements are suppressed. Here, we show that tyramine inhibits head movements and forward locomotion through the activation of a tyramine-gated chloride channel, LGC-55. lgc-55 mutant animals have defects in reversal behavior and fail to suppress head oscillations in response to anterior touch. lgc-55 is expressed in neurons and muscle cells that receive direct synaptic inputs from tyraminergic motor neurons. Therefore, tyramine can act as a classical inhibitory neurotransmitter. Activation of LGC-55 by tyramine coordinates the output of two distinct motor programs, locomotion and head movements that are critical for a C. elegans escape response."xsd:string |
| http://purl.uniprot.org/citations/19477154 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.neuron.2009.04.013"xsd:string |
| http://purl.uniprot.org/citations/19477154 | http://purl.uniprot.org/core/author | "Francis M.M."xsd:string |
| http://purl.uniprot.org/citations/19477154 | http://purl.uniprot.org/core/author | "Alkema M.J."xsd:string |
| http://purl.uniprot.org/citations/19477154 | http://purl.uniprot.org/core/author | "Donnelly J.L."xsd:string |
| http://purl.uniprot.org/citations/19477154 | http://purl.uniprot.org/core/author | "McPherson A.D."xsd:string |
| http://purl.uniprot.org/citations/19477154 | http://purl.uniprot.org/core/author | "Pirri J.K."xsd:string |
| http://purl.uniprot.org/citations/19477154 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19477154 | http://purl.uniprot.org/core/name | "Neuron"xsd:string |
| http://purl.uniprot.org/citations/19477154 | http://purl.uniprot.org/core/pages | "526-538"xsd:string |
| http://purl.uniprot.org/citations/19477154 | http://purl.uniprot.org/core/title | "A tyramine-gated chloride channel coordinates distinct motor programs of a Caenorhabditis elegans escape response."xsd:string |
| http://purl.uniprot.org/citations/19477154 | http://purl.uniprot.org/core/volume | "62"xsd:string |
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