| http://purl.uniprot.org/citations/19508346 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19508346 | http://www.w3.org/2000/01/rdf-schema#comment | "Nogo-A, a neurite outgrowth inhibitor, is expressed exclusively on oligodendrocytes and neurons in the CNS. The central domain of Amino-Nogo spanning amino acids 567-748 in the human Nogo-A designated NIG, mediates persistent inhibition of axonal outgrowth and induces growth cone collapse by signaling through an as yet unidentified NIG receptor. We identified 82 NIG-interacting proteins by screening a high-density human protein microarray composed of 5000 proteins with a recombinant NIG protein as a probe. Following an intensive database search, we selected 12 neuron/oligodendrocyte-associated NIG interactors. Among them, we verified the molecular interaction of NIG with 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNP), a cell type-specific marker of oligodendrocytes, by immunoprecipitation and cell imaging analysis. Although CNP located chiefly in the cytoplasm of oligodendrocytes might not serve as a cell-surface NIG receptor, it could act as a conformational stabilizer for the intrinsically unstructured large segment of Amino-Nogo."xsd:string |
| http://purl.uniprot.org/citations/19508346 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1440-1789.2009.01035.x"xsd:string |
| http://purl.uniprot.org/citations/19508346 | http://purl.uniprot.org/core/author | "Arima K."xsd:string |
| http://purl.uniprot.org/citations/19508346 | http://purl.uniprot.org/core/author | "Satoh J."xsd:string |
| http://purl.uniprot.org/citations/19508346 | http://purl.uniprot.org/core/author | "Tabunoki H."xsd:string |
| http://purl.uniprot.org/citations/19508346 | http://purl.uniprot.org/core/author | "Obayashi S."xsd:string |
| http://purl.uniprot.org/citations/19508346 | http://purl.uniprot.org/core/author | "Sumiyoshi K."xsd:string |
| http://purl.uniprot.org/citations/19508346 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/19508346 | http://purl.uniprot.org/core/name | "Neuropathology"xsd:string |
| http://purl.uniprot.org/citations/19508346 | http://purl.uniprot.org/core/pages | "7-14"xsd:string |
| http://purl.uniprot.org/citations/19508346 | http://purl.uniprot.org/core/title | "Protein microarray analysis identifies cyclic nucleotide phosphodiesterase as an interactor of Nogo-A."xsd:string |
| http://purl.uniprot.org/citations/19508346 | http://purl.uniprot.org/core/volume | "30"xsd:string |
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