http://purl.uniprot.org/citations/19525955 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19525955 | http://www.w3.org/2000/01/rdf-schema#comment | "To identify multiple sclerosis (MS) susceptibility loci, we conducted a genome-wide association study (GWAS) in 1,618 cases and used shared data for 3,413 controls. We performed replication in an independent set of 2,256 cases and 2,310 controls, for a total of 3,874 cases and 5,723 controls. We identified risk-associated SNPs on chromosome 12q13-14 (rs703842, P = 5.4 x 10(-11); rs10876994, P = 2.7 x 10(-10); rs12368653, P = 1.0 x 10(-7)) and upstream of CD40 on chromosome 20q13 (rs6074022, P = 1.3 x 10(-7); rs1569723, P = 2.9 x 10(-7)). Both loci are also associated with other autoimmune diseases. We also replicated several known MS associations (HLA-DR15, P = 7.0 x 10(-184); CD58, P = 9.6 x 10(-8); EVI5-RPL5, P = 2.5 x 10(-6); IL2RA, P = 7.4 x 10(-6); CLEC16A, P = 1.1 x 10(-4); IL7R, P = 1.3 x 10(-3); TYK2, P = 3.5 x 10(-3)) and observed a statistical interaction between SNPs in EVI5-RPL5 and HLA-DR15 (P = 0.001)."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng.396"xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Brown M.A."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Clarke G."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Foote S.J."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Field J."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Chapman C."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Bahlo M."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Scott R.J."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Johnson L.J."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Mason D."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Danoy P."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Booth D.R."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Broadley S.A."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Taylor B.V."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Perera D."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "McMorran B.J."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Butzkueven H."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Carroll W.M."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Cox M.B."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Heard R.N."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Kermode A.G."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Kilpatrick T.J."xsd:string |
http://purl.uniprot.org/citations/19525955 | http://purl.uniprot.org/core/author | "Marriott M."xsd:string |