| http://purl.uniprot.org/citations/19533040 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19533040 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19533040 | http://www.w3.org/2000/01/rdf-schema#comment | "We previously identified cancer-upregulated gene 2 (CUG2) as a commonly up-regulated gene in various human cancer tissues, especially in ovary, liver, and lung (Lee et al., 2007a). CUG2 was determined to be a nuclear protein that exhibited high proto-oncogenic activities when overexpressed in NIH3T3 mouse fibroblast cells. To identify other cellular functions of CUG2, we performed yeast two-hybrid screening and identified CENP-T, a component of CENP-A nucleosome complex in the centromere, as an interacting partner of CUG2. Moreover, CENP-A, the principle centromeric determinant, was also found in complex with CENP-T/CUG2. Immunofluorescent staining revealed the co-localization of CUG2 with human centromeric markers. Inhibition of CUG2 expression drastically affected cell viability by inducing aberrant cell division. We propose that CUG2 is a new component of the human centromeric complex that is required for proper chromosome segregation during mitosis."xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.org/dc/terms/identifier | "doi:10.1007/s10059-009-0083-2"xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.org/dc/terms/identifier | "doi:10.1007/s10059-009-0083-2"xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Lee M."xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Lee M."xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Lee S."xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Lee S."xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Kim H."xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Kim H."xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Lee D.J."xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Lee D.J."xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Park B."xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Park B."xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Koh W."xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Koh W."xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Lee S.'"xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Lee S.'"xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Lim D.S."xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/author | "Lim D.S."xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/name | "Mol. Cells"xsd:string |
| http://purl.uniprot.org/citations/19533040 | http://purl.uniprot.org/core/name | "Mol. Cells"xsd:string |