| http://purl.uniprot.org/citations/19536132 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19536132 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19536132 | http://www.w3.org/2000/01/rdf-schema#comment | "The crucial roles of Sec1/Munc18 (SM)-like proteins in membrane fusion have been evidenced in genetic and biochemical studies. SM proteins interact directly with SNAREs and contribute to SNARE pairing by a yet unclear mechanism. Here, we show that the SM protein, Sly1, interacts directly with the conserved oligomeric Golgi (COG) tethering complex. The Sly1-COG interaction is mediated by the Cog4 subunit, which also interacts with Syntaxin 5 through a different binding site. We provide evidence that disruption of Cog4-Sly1 interaction impairs pairing of SNAREs involved in intra-Golgi transport thereby markedly attenuating Golgi-to-ER retrograde transport. These results highlight the mechanism by which SM proteins link tethering to SNAREpin assembly."xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.org/dc/terms/identifier | "doi:10.1038/emboj.2009.168"xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.org/dc/terms/identifier | "doi:10.1038/emboj.2009.168"xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/author | "Hong W."xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/author | "Hong W."xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/author | "Lev S."xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/author | "Lev S."xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/author | "Laufman O."xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/author | "Laufman O."xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/author | "Kedan A."xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/author | "Kedan A."xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/pages | "2006-2017"xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/pages | "2006-2017"xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/title | "Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing."xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/title | "Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing."xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/volume | "28"xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://purl.uniprot.org/core/volume | "28"xsd:string |
| http://purl.uniprot.org/citations/19536132 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19536132 |
| http://purl.uniprot.org/citations/19536132 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19536132 |