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http://purl.uniprot.org/citations/19541371http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19541371http://www.w3.org/2000/01/rdf-schema#comment"Interferon-beta (IFN-beta), acting canonically via the modulation of transcription, affects neocortical pyramidal neurons. By use of 2-D differential gel electrophoresis and subsequent mass spectrometry we identified IFN-beta regulated proteins in the central nervous system. These proteins are involved in cytoskeleton assembly, protein transport and nucleotide metabolism and, as such, serve regenerative and protective functions. Electrophysiologically, IFN-beta mediated protein synthesis is essential for part of the excitatory neuronal effects, as revealed under blockade of protein biosynthesis. This study presents novel effects of IFN-beta in the central nervous system and begins to unravel the mechanism behind the known excitability changes in neurons."xsd:string
http://purl.uniprot.org/citations/19541371http://purl.org/dc/terms/identifier"doi:10.1016/j.jneuroim.2009.06.004"xsd:string
http://purl.uniprot.org/citations/19541371http://purl.uniprot.org/core/author"Stadler K."xsd:string
http://purl.uniprot.org/citations/19541371http://purl.uniprot.org/core/author"Rolfs A."xsd:string
http://purl.uniprot.org/citations/19541371http://purl.uniprot.org/core/author"Beyer S."xsd:string
http://purl.uniprot.org/citations/19541371http://purl.uniprot.org/core/author"Scharf C."xsd:string
http://purl.uniprot.org/citations/19541371http://purl.uniprot.org/core/author"Strauss U."xsd:string
http://purl.uniprot.org/citations/19541371http://purl.uniprot.org/core/author"Mix E."xsd:string
http://purl.uniprot.org/citations/19541371http://purl.uniprot.org/core/author"Hoffrogge R."xsd:string
http://purl.uniprot.org/citations/19541371http://purl.uniprot.org/core/author"Raether G."xsd:string
http://purl.uniprot.org/citations/19541371http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19541371http://purl.uniprot.org/core/name"J Neuroimmunol"xsd:string
http://purl.uniprot.org/citations/19541371http://purl.uniprot.org/core/pages"31-38"xsd:string
http://purl.uniprot.org/citations/19541371http://purl.uniprot.org/core/title"Interferon-beta modulates protein synthesis in the central nervous system."xsd:string
http://purl.uniprot.org/citations/19541371http://purl.uniprot.org/core/volume"213"xsd:string
http://purl.uniprot.org/citations/19541371http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19541371
http://purl.uniprot.org/citations/19541371http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19541371
http://purl.uniprot.org/uniprot/#_P70499-mappedCitation-19541371http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19541371
http://purl.uniprot.org/uniprot/#_A0A7R8GV74-mappedCitation-19541371http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19541371
http://purl.uniprot.org/uniprot/A0A7R8GV74http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/19541371
http://purl.uniprot.org/uniprot/P70499http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/19541371