| http://purl.uniprot.org/citations/19544111 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19544111 | http://www.w3.org/2000/01/rdf-schema#comment | "O(6)-methylguanine-DNA methyltransferase (MGMT) is a DNA repair enzyme that removes alkyl groups from the O(6) position of guanine. MGMT is transcriptionally silenced by promoter hypermethylation in several human neoplasia. We used methylation-specific PCR (MSP) to analyze the MGMT promoter methylation status of 50 glioblastoma tumors. Hypermethylation was detected in 24 of 50 (48%) samples. We also analyzed mutant p53 expression by immunohistochemical analysis of glioblastoma tissue samples. A significant association was found between MGMT methylation and p53 mutation status (p< .05). These results suggested that epigenetic inactivation of MGMT plays an important role in the survival of glioblastoma patients and this inactivated gene involved in p53 mutation."xsd:string |
| http://purl.uniprot.org/citations/19544111 | http://purl.org/dc/terms/identifier | "doi:10.1080/07357900902783211"xsd:string |
| http://purl.uniprot.org/citations/19544111 | http://purl.uniprot.org/core/author | "Sharif S."xsd:string |
| http://purl.uniprot.org/citations/19544111 | http://purl.uniprot.org/core/author | "Rahighi S."xsd:string |
| http://purl.uniprot.org/citations/19544111 | http://purl.uniprot.org/core/author | "Behravan J."xsd:string |
| http://purl.uniprot.org/citations/19544111 | http://purl.uniprot.org/core/author | "Moradi A."xsd:string |
| http://purl.uniprot.org/citations/19544111 | http://purl.uniprot.org/core/author | "Lotfi M."xsd:string |
| http://purl.uniprot.org/citations/19544111 | http://purl.uniprot.org/core/author | "Ghaffarzadegan K."xsd:string |
| http://purl.uniprot.org/citations/19544111 | http://purl.uniprot.org/core/author | "Raziee H.R."xsd:string |
| http://purl.uniprot.org/citations/19544111 | http://purl.uniprot.org/core/author | "Afsharnezhad S."xsd:string |
| http://purl.uniprot.org/citations/19544111 | http://purl.uniprot.org/core/author | "Shamsara J."xsd:string |
| http://purl.uniprot.org/citations/19544111 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19544111 | http://purl.uniprot.org/core/name | "Cancer Invest"xsd:string |
| http://purl.uniprot.org/citations/19544111 | http://purl.uniprot.org/core/pages | "825-829"xsd:string |
| http://purl.uniprot.org/citations/19544111 | http://purl.uniprot.org/core/title | "Association between MGMT promoter hypermethylation and p53 mutation in glioblastoma."xsd:string |
| http://purl.uniprot.org/citations/19544111 | http://purl.uniprot.org/core/volume | "27"xsd:string |
| http://purl.uniprot.org/citations/19544111 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19544111 |
| http://purl.uniprot.org/citations/19544111 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19544111 |
| http://purl.uniprot.org/uniprot/#_A0A0M4B4Y9-mappedCitation-19544111 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19544111 |
| http://purl.uniprot.org/uniprot/#_A0A087WXZ1-mappedCitation-19544111 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19544111 |
| http://purl.uniprot.org/uniprot/#_A0A087X1Q1-mappedCitation-19544111 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19544111 |
| http://purl.uniprot.org/uniprot/#_A0A0C4KX50-mappedCitation-19544111 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19544111 |
| http://purl.uniprot.org/uniprot/#_A0A0C4L134-mappedCitation-19544111 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19544111 |
| http://purl.uniprot.org/uniprot/#_A0A059PXT9-mappedCitation-19544111 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19544111 |