| http://purl.uniprot.org/citations/1956401 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1956401 | http://www.w3.org/2000/01/rdf-schema#comment | "HLA class II molecules are heterodimeric transmembrane glycoproteins that bind and present processed antigenic peptides to CD4-positive T lymphocytes. Intracellularly, class II molecules associate with a third subunit termed the invariant (I) chain. Here we describe the physical characteristics of the intracellular class II alpha beta I complex. Chemical crosslinking, size exclusion chromatography and sedimentation velocity studies demonstrate that the alpha beta I complex is a nine-subunit transmembrane protein that contains three alpha beta dimers associated with an I chain trimer. The organization of class II alpha- and beta-subunits in such a multimer may have a role in the documented ability of the I chain to inhibit peptide binding to class II molecules. In addition, the formation of the nine-chain complex may induce the structural changes necessary to overcome the cytoplasmic retention signal responsible for the localization of free I chain in the endoplasmic reticulum, releasing class II-I chain complexes for transport to endosomes."xsd:string |
| http://purl.uniprot.org/citations/1956401 | http://purl.org/dc/terms/identifier | "doi:10.1038/354392a0"xsd:string |
| http://purl.uniprot.org/citations/1956401 | http://purl.uniprot.org/core/author | "Marks M.S."xsd:string |
| http://purl.uniprot.org/citations/1956401 | http://purl.uniprot.org/core/author | "Cresswell P."xsd:string |
| http://purl.uniprot.org/citations/1956401 | http://purl.uniprot.org/core/author | "Roche P.A."xsd:string |
| http://purl.uniprot.org/citations/1956401 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
| http://purl.uniprot.org/citations/1956401 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
| http://purl.uniprot.org/citations/1956401 | http://purl.uniprot.org/core/pages | "392-394"xsd:string |
| http://purl.uniprot.org/citations/1956401 | http://purl.uniprot.org/core/title | "Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain."xsd:string |
| http://purl.uniprot.org/citations/1956401 | http://purl.uniprot.org/core/volume | "354"xsd:string |
| http://purl.uniprot.org/citations/1956401 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1956401 |
| http://purl.uniprot.org/citations/1956401 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1956401 |
| http://purl.uniprot.org/uniprot/#_P13762-mappedCitation-1956401 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1956401 |
| http://purl.uniprot.org/uniprot/#_P20036-mappedCitation-1956401 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1956401 |
| http://purl.uniprot.org/uniprot/#_P79483-mappedCitation-1956401 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1956401 |
| http://purl.uniprot.org/uniprot/#_P04233-mappedCitation-1956401 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1956401 |
| http://purl.uniprot.org/uniprot/#_Q30154-mappedCitation-1956401 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1956401 |
| http://purl.uniprot.org/uniprot/#_P01903-mappedCitation-1956401 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1956401 |
| http://purl.uniprot.org/uniprot/#_P04440-mappedCitation-1956401 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1956401 |
| http://purl.uniprot.org/uniprot/#_P05538-mappedCitation-1956401 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1956401 |
| http://purl.uniprot.org/uniprot/#_P01906-mappedCitation-1956401 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1956401 |
| http://purl.uniprot.org/uniprot/#_P01909-mappedCitation-1956401 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1956401 |
| http://purl.uniprot.org/uniprot/#_P01911-mappedCitation-1956401 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1956401 |
| http://purl.uniprot.org/uniprot/#_P01920-mappedCitation-1956401 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1956401 |