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http://purl.uniprot.org/citations/1956404http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1956404http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1956404http://www.w3.org/2000/01/rdf-schema#comment"A general initiation factor, TFIIE, is essential for transcription initiation by RNA polymerase II in conjunction with other general factors. TFIIE is a heterotetramer containing two subunits of relative molecular mass 57,000 (TFIIE-alpha) and two of 34,000 (TFIIE-beta). TFIIE-beta is required in conjunction with TFIIE-alpha for transcription initiation. Here we report the cloning and expression of a complementary DNA encoding a functional human TFIIE-beta. Recombinant TFIIE-beta could replace the natural TFIIE-beta for transcription in conjunction with TFIIE-alpha. Amino-acid sequence comparisons reveal regions with sequence similarities to: subregion 3 of bacterial sigma factors; a region of RAP30 (the small subunit of TFIIF) with sequence similarity to a sigma-factor subregion implicated in binding to RNA polymerase; and a portion of the basic region-helix-loop-helix motif found in several enhancer-binding proteins. These potential homologies have implications for the role of TFIIE in preinitiation complex assembly and function."xsd:string
http://purl.uniprot.org/citations/1956404http://purl.org/dc/terms/identifier"doi:10.1038/354401a0"xsd:string
http://purl.uniprot.org/citations/1956404http://purl.org/dc/terms/identifier"doi:10.1038/354401a0"xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/author"Kato H."xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/author"Kato H."xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/author"Horikoshi M."xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/author"Horikoshi M."xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/author"Shimasaki S."xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/author"Shimasaki S."xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/author"Roeder R.G."xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/author"Roeder R.G."xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/author"Ohkuma Y."xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/author"Ohkuma Y."xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/author"Sumimoto H."xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/author"Sumimoto H."xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/author"Sinn E."xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/author"Sinn E."xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/name"Nature"xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/name"Nature"xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/pages"401-404"xsd:string
http://purl.uniprot.org/citations/1956404http://purl.uniprot.org/core/pages"401-404"xsd:string