| http://purl.uniprot.org/citations/19578363 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19578363 | http://www.w3.org/2000/01/rdf-schema#comment | "In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC), we describe here several new susceptibility variants. SNP rs11170164, encoding a G138E substitution in the keratin 5 (KRT5) gene, affects risk of BCC (OR = 1.35, P = 2.1 x 10(-9)). A variant at 9p21 near CDKN2A and CDKN2B also confers susceptibility to BCC (rs2151280[C]; OR = 1.19, P = 6.9 x 10(-9)), as does rs157935[T] at 7q32 near the imprinted gene KLF14 (OR = 1.23, P = 5.7 x 10(-10)). The effect of rs157935[T] is dependent on the parental origin of the risk allele. None of these variants were found to be associated with melanoma or fair-pigmentation traits. A melanoma- and pigmentation-associated variant in the SLC45A2 gene, L374F, is associated with risk of both BCC and squamous cell carcinoma. Finally, we report conclusive evidence that rs401681[C] in the TERT-CLPTM1L locus confers susceptibility to BCC but protects against melanoma."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng.412"xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Kumar R."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Wendt J."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Blondal T."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Scherer D."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Gudjonsson S.A."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Kong A."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Stefansson K."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Sulem P."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Bjornsdottir G."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Gudbjartsson D.F."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Gudmundsson J."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Gulcher J.R."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Jakobsdottir M."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Kiemeney L.A."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Kristjansson K."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Mayordomo J.I."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Rafnar T."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Rudnai P."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Saemundsdottir J."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Saez B."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Stacey S.N."xsd:string |
| http://purl.uniprot.org/citations/19578363 | http://purl.uniprot.org/core/author | "Thorleifsson G."xsd:string |