| http://purl.uniprot.org/citations/19589780 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19589780 | http://www.w3.org/2000/01/rdf-schema#comment | "Epstein-Barr virus, a ubiquitous human herpesvirus, is associated with the development of carcinomas and lymphomas. We previously showed that transforming growth factor beta1 (TGF-beta1) mediated the virus to enter the lytic cycle, which is triggered by expression of Z Epstein-Barr virus replication activator (ZEBRA), through the ERK 1/2 MAPK signaling pathway. We report here that Akt, activated downstream from ERK 1/2, was required for TGF-beta1-induced ZEBRA expression and enabled Smad3, a mediator of TGF-beta1 signaling, to be acetylated by direct interaction with the co-activator CREB-binding protein and then to regulate TGF-beta1-induced ZEBRA expression."xsd:string |
| http://purl.uniprot.org/citations/19589780 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m109.036483"xsd:string |
| http://purl.uniprot.org/citations/19589780 | http://purl.uniprot.org/core/author | "Zhang W."xsd:string |
| http://purl.uniprot.org/citations/19589780 | http://purl.uniprot.org/core/author | "Cole P."xsd:string |
| http://purl.uniprot.org/citations/19589780 | http://purl.uniprot.org/core/author | "Joab I."xsd:string |
| http://purl.uniprot.org/citations/19589780 | http://purl.uniprot.org/core/author | "Khelifa R."xsd:string |
| http://purl.uniprot.org/citations/19589780 | http://purl.uniprot.org/core/author | "Ramirez V."xsd:string |
| http://purl.uniprot.org/citations/19589780 | http://purl.uniprot.org/core/author | "Meyers D."xsd:string |
| http://purl.uniprot.org/citations/19589780 | http://purl.uniprot.org/core/author | "Oussaief L."xsd:string |
| http://purl.uniprot.org/citations/19589780 | http://purl.uniprot.org/core/author | "Hippocrate A."xsd:string |
| http://purl.uniprot.org/citations/19589780 | http://purl.uniprot.org/core/author | "Rampanou A."xsd:string |
| http://purl.uniprot.org/citations/19589780 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19589780 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/19589780 | http://purl.uniprot.org/core/pages | "23912-23924"xsd:string |
| http://purl.uniprot.org/citations/19589780 | http://purl.uniprot.org/core/title | "Phosphatidylinositol 3-kinase/Akt pathway targets acetylation of Smad3 through Smad3/CREB-binding protein interaction: contribution to transforming growth factor beta1-induced Epstein-Barr virus reactivation."xsd:string |
| http://purl.uniprot.org/citations/19589780 | http://purl.uniprot.org/core/volume | "284"xsd:string |
| http://purl.uniprot.org/citations/19589780 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19589780 |
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| http://purl.uniprot.org/uniprot/#_A0A510GAF6-mappedCitation-19589780 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19589780 |