| http://purl.uniprot.org/citations/19592656 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19592656 | http://www.w3.org/2000/01/rdf-schema#comment | "Fas apoptosis inhibitory molecule (FAIM) was cloned as a mediator of Fas resistance that is highly evolutionarily conserved but contains no known effector motifs. In this study, we report entirely new functions of FAIM that regulate B cell signaling and differentiation. FAIM acts to specifically enhance CD40 signaling for NF-kappaB activation, IRF-4 expression, and BCL-6 down-regulation in vitro, but has no effect on its own or in conjunction with LPS or anti-Ig stimulation. In keeping with its effects on IRF-4 and BCL-6, FAIM overexpression augments the plasma cell compartment in vivo. These results indicate that FAIM is a new player on the field of B cell differentiation and acts as a force multiplier for a series of events that begins with CD40 engagement and ends with plasma cell differentiation."xsd:string |
| http://purl.uniprot.org/citations/19592656 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.0900056"xsd:string |
| http://purl.uniprot.org/citations/19592656 | http://purl.uniprot.org/core/author | "Kaku H."xsd:string |
| http://purl.uniprot.org/citations/19592656 | http://purl.uniprot.org/core/author | "Rothstein T.L."xsd:string |
| http://purl.uniprot.org/citations/19592656 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19592656 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/19592656 | http://purl.uniprot.org/core/pages | "1667-1674"xsd:string |
| http://purl.uniprot.org/citations/19592656 | http://purl.uniprot.org/core/title | "Fas apoptosis inhibitory molecule enhances CD40 signaling in B cells and augments the plasma cell compartment."xsd:string |
| http://purl.uniprot.org/citations/19592656 | http://purl.uniprot.org/core/volume | "183"xsd:string |
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| http://purl.uniprot.org/citations/19592656 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19592656 |
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| http://purl.uniprot.org/uniprot/#_A0A0S2Z3C7-mappedCitation-19592656 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19592656 |
| http://purl.uniprot.org/uniprot/#_A0A8Q3SI60-mappedCitation-19592656 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19592656 |
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| http://purl.uniprot.org/uniprot/#_Q59F01-mappedCitation-19592656 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19592656 |
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| http://purl.uniprot.org/uniprot/#_Q9WUD8-mappedCitation-19592656 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19592656 |