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http://purl.uniprot.org/citations/19631389http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19631389http://www.w3.org/2000/01/rdf-schema#comment"Human leukocyte antigen-C (HLA-C) is the only polymorphic classical histocompatibility antigen expressed by fetal trophoblasts at the fetal-maternal interface. Interactions between HLA-C and decidual natural killer (NK) cells may facilitate trophoblast invasion into maternal tissue. Thus far no evidence has been provided that decidual T cells specifically recognize and respond to fetal alloantigens at the fetal-maternal interface. In this study, we show that pregnancies containing a HLA-C mismatched child induce an increased percentage of CD4(+)CD25(dim) activated T cells in decidual tissue. In addition, HLA-C mismatched pregnancies exhibit a decidual lymphocyte response to fetal cells and contain functional CD4(+)CD25(bright) regulatory T cells in decidual tissue, whereas HLA-C matched pregnancies do not. This suggests that decidual T cells specifically recognize fetal HLA-C at the fetal-maternal interface but are prevented from inducing a destructive immune response in uncomplicated pregnancies."xsd:string
http://purl.uniprot.org/citations/19631389http://purl.org/dc/terms/identifier"doi:10.1016/j.jri.2009.05.003"xsd:string
http://purl.uniprot.org/citations/19631389http://purl.uniprot.org/core/author"Claas F.H."xsd:string
http://purl.uniprot.org/citations/19631389http://purl.uniprot.org/core/author"Scherjon S.A."xsd:string
http://purl.uniprot.org/citations/19631389http://purl.uniprot.org/core/author"Tilburgs T."xsd:string
http://purl.uniprot.org/citations/19631389http://purl.uniprot.org/core/author"van Rood J.J."xsd:string
http://purl.uniprot.org/citations/19631389http://purl.uniprot.org/core/author"Haasnoot G.W."xsd:string
http://purl.uniprot.org/citations/19631389http://purl.uniprot.org/core/author"Roelen D.L."xsd:string
http://purl.uniprot.org/citations/19631389http://purl.uniprot.org/core/author"van der Mast B.J."xsd:string
http://purl.uniprot.org/citations/19631389http://purl.uniprot.org/core/author"Versteeg-V D Voort-Maarschalk M."xsd:string
http://purl.uniprot.org/citations/19631389http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19631389http://purl.uniprot.org/core/name"J Reprod Immunol"xsd:string
http://purl.uniprot.org/citations/19631389http://purl.uniprot.org/core/pages"148-157"xsd:string
http://purl.uniprot.org/citations/19631389http://purl.uniprot.org/core/title"Fetal-maternal HLA-C mismatch is associated with decidual T cell activation and induction of functional T regulatory cells."xsd:string
http://purl.uniprot.org/citations/19631389http://purl.uniprot.org/core/volume"82"xsd:string
http://purl.uniprot.org/citations/19631389http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19631389
http://purl.uniprot.org/citations/19631389http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19631389
http://purl.uniprot.org/uniprot/#_A0A0A7C549-mappedCitation-19631389http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19631389
http://purl.uniprot.org/uniprot/#_A0A0A7C553-mappedCitation-19631389http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19631389
http://purl.uniprot.org/uniprot/#_A0A089N0V0-mappedCitation-19631389http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19631389
http://purl.uniprot.org/uniprot/#_A0A0A7C850-mappedCitation-19631389http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19631389
http://purl.uniprot.org/uniprot/#_A0A0A7C8P1-mappedCitation-19631389http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19631389
http://purl.uniprot.org/uniprot/#_A0A0A7C8P4-mappedCitation-19631389http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19631389
http://purl.uniprot.org/uniprot/#_A0A0A7C8P8-mappedCitation-19631389http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19631389