| http://purl.uniprot.org/citations/19635462 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19635462 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19635462 | http://www.w3.org/2000/01/rdf-schema#comment | "Two isoforms of adenosine kinase (AdK) have been identified in mammalian organisms with the long isoform (AdK-long) containing extra 20-21 amino acids at the N-terminus (NTS). The subcellular localizations of these isoforms are not known and they contain no identifiable targeting sequence. Immunofluorescence labeling of mammalian cells expressing either only AdK-long or both isoforms with AdK-specific antibody showed only nuclear labeling or both nucleus and cytoplasmic labeling, respectively. The AdK-long and -short isoforms fused at the C-terminus with c-myc epitope also localized in the nucleus and cytoplasm, respectively. Fusion of the AdK-long NTS to green fluorescent protein also resulted in its nuclear localization. AdK-long NTS contains a cluster of conserved amino acids (PKPKKLKVE). Replacement of KK in this sequence with either AA or AD abolished its nuclear localization capability, indicating that this cluster likely serves as a nuclear localization signal. AdK in nucleus is likely required for sustaining methylation reactions."xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2009.07.106"xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2009.07.106"xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/author | "Park J."xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/author | "Park J."xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/author | "Gupta R.S."xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/author | "Gupta R.S."xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/author | "Singh B."xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/author | "Singh B."xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/author | "Cui X.A."xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/author | "Cui X.A."xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/pages | "46-50"xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/pages | "46-50"xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/title | "Subcellular localization of adenosine kinase in mammalian cells: The long isoform of AdK is localized in the nucleus."xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/title | "Subcellular localization of adenosine kinase in mammalian cells: The long isoform of AdK is localized in the nucleus."xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/volume | "388"xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://purl.uniprot.org/core/volume | "388"xsd:string |
| http://purl.uniprot.org/citations/19635462 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19635462 |
| http://purl.uniprot.org/citations/19635462 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19635462 |