| http://purl.uniprot.org/citations/19648240 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19648240 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19648240 | http://www.w3.org/2000/01/rdf-schema#comment | "A survey of chromosomal variation in the ST239 clonal group of methicillin-resistant Staphylococcus aureus (MRSA) revealed a novel genetic element, ICE6013. The element is 13,354 bp in length, excluding a 6,551-bp Tn552 insertion. ICE6013 is flanked by 3-bp direct repeats and is demarcated by 8-bp imperfect inverted repeats. The element was present in 6 of 15 genome-sequenced S. aureus strains, and it was detected using genetic markers in 19 of 44 diverse MRSA and methicillin-susceptible strains and in all 111 ST239 strains tested. Low integration site specificity was discerned. Multiple chromosomal copies and the presence of extrachromosomal circular forms of ICE6013 were detected in various strains. The circular forms included 3-bp coupling sequences, located between the 8-bp ends of the element, that corresponded to the 3-bp direct repeats flanking the chromosomal forms. ICE6013 is predicted to encode 15 open reading frames, including an IS30-like DDE transposase in place of a Tyr/Ser recombinase and homologs of gram-positive bacterial conjugation components. Further sequence analyses indicated that ICE6013 is more closely related to ICEBs1 from Bacillus subtilis than to the only other potential integrative conjugative element known from S. aureus, Tn5801. Evidence of recombination between ICE6013 elements is also presented. In summary, ICE6013 is the first member of a new family of active, integrative genetic elements that are widely dispersed within S. aureus strains."xsd:string |
| http://purl.uniprot.org/citations/19648240 | http://purl.org/dc/terms/identifier | "doi:10.1128/JB.00352-09"xsd:string |
| http://purl.uniprot.org/citations/19648240 | http://purl.org/dc/terms/identifier | "doi:10.1128/jb.00352-09"xsd:string |
| http://purl.uniprot.org/citations/19648240 | http://purl.uniprot.org/core/author | "Robinson D.A."xsd:string |
| http://purl.uniprot.org/citations/19648240 | http://purl.uniprot.org/core/author | "Robinson D.A."xsd:string |
| http://purl.uniprot.org/citations/19648240 | http://purl.uniprot.org/core/author | "Smyth D.S."xsd:string |
| http://purl.uniprot.org/citations/19648240 | http://purl.uniprot.org/core/author | "Smyth D.S."xsd:string |
| http://purl.uniprot.org/citations/19648240 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19648240 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19648240 | http://purl.uniprot.org/core/name | "J. Bacteriol."xsd:string |
| http://purl.uniprot.org/citations/19648240 | http://purl.uniprot.org/core/name | "J Bacteriol"xsd:string |
| http://purl.uniprot.org/citations/19648240 | http://purl.uniprot.org/core/pages | "5964-5975"xsd:string |
| http://purl.uniprot.org/citations/19648240 | http://purl.uniprot.org/core/pages | "5964-5975"xsd:string |
| http://purl.uniprot.org/citations/19648240 | http://purl.uniprot.org/core/title | "Integrative and sequence characteristics of a novel genetic element, ICE6013, in Staphylococcus aureus."xsd:string |
| http://purl.uniprot.org/citations/19648240 | http://purl.uniprot.org/core/title | "Integrative and sequence characteristics of a novel genetic element, ICE6013, in Staphylococcus aureus."xsd:string |
| http://purl.uniprot.org/citations/19648240 | http://purl.uniprot.org/core/volume | "191"xsd:string |
| http://purl.uniprot.org/citations/19648240 | http://purl.uniprot.org/core/volume | "191"xsd:string |
| http://purl.uniprot.org/citations/19648240 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19648240 |
| http://purl.uniprot.org/citations/19648240 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19648240 |
| http://purl.uniprot.org/citations/19648240 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19648240 |
| http://purl.uniprot.org/citations/19648240 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19648240 |
| http://purl.uniprot.org/uniprot/B6V379 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/19648240 |
| http://purl.uniprot.org/uniprot/B6V388 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/19648240 |