| http://purl.uniprot.org/citations/19654074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19654074 | http://www.w3.org/2000/01/rdf-schema#comment | "Anti-glomerular basement membrane (GBM) disease, a rare autoimmune disorder, is associated with HLA-DR15 genotype in Caucasian and Japanese populations. But the distribution of HLA-DRB1 alleles in Chinese patients with anti-GBM disease and their association with clinical characteristics of anti-GBM disease are to be determined. The present study analyzed the HLA-DRB1 alleles by sequence based typing in 44 Chinese patients with anti-GBM disease and 200 healthy controls. The effects of DRB1 alleles on susceptibility to anti-GBM disease were examined by a relative predispositional effects (RPEs) method. The clinical and pathological data of the patients were collected and analyzed. The DRB1*1501 allele was significantly associated with anti-GBM disease (p=1.597 x 10(-7)). The RPEs test also showed a significant increased frequency of DRB1*0404 in anti-GBM disease (p=0.037). Interestingly, the patients with DRB1*1501 or 0404 had more crescent formation in glomeruli than those without the two alleles (p=0.021). But the DRB1*0404 was rare in both patients and control groups, which indicates that the importance of the *0404 allele is limited in anti-GBM disease. We conclude that the HLA-DRB1*1501 allele is a genetic marker for susceptibility to anti-GBM disease."xsd:string |
| http://purl.uniprot.org/citations/19654074 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.clim.2009.07.005"xsd:string |
| http://purl.uniprot.org/citations/19654074 | http://purl.uniprot.org/core/author | "Cui Z."xsd:string |
| http://purl.uniprot.org/citations/19654074 | http://purl.uniprot.org/core/author | "Yang R."xsd:string |
| http://purl.uniprot.org/citations/19654074 | http://purl.uniprot.org/core/author | "Zhao J."xsd:string |
| http://purl.uniprot.org/citations/19654074 | http://purl.uniprot.org/core/author | "Zhao M.H."xsd:string |
| http://purl.uniprot.org/citations/19654074 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19654074 | http://purl.uniprot.org/core/name | "Clin Immunol"xsd:string |
| http://purl.uniprot.org/citations/19654074 | http://purl.uniprot.org/core/pages | "245-250"xsd:string |
| http://purl.uniprot.org/citations/19654074 | http://purl.uniprot.org/core/title | "The role of HLA-DRB1 alleles on susceptibility of Chinese patients with anti-GBM disease."xsd:string |
| http://purl.uniprot.org/citations/19654074 | http://purl.uniprot.org/core/volume | "133"xsd:string |
| http://purl.uniprot.org/citations/19654074 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19654074 |
| http://purl.uniprot.org/citations/19654074 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19654074 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-19654074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19654074 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-19654074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19654074 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-19654074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19654074 |
| http://purl.uniprot.org/uniprot/#_A0A0A0WDZ3-mappedCitation-19654074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19654074 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DD60-mappedCitation-19654074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19654074 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DD66-mappedCitation-19654074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19654074 |
| http://purl.uniprot.org/uniprot/#_A0A141AZI1-mappedCitation-19654074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19654074 |
| http://purl.uniprot.org/uniprot/#_A0A141AZI3-mappedCitation-19654074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19654074 |
| http://purl.uniprot.org/uniprot/#_A0A141AZI4-mappedCitation-19654074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19654074 |
| http://purl.uniprot.org/uniprot/#_A0A0A0WAE5-mappedCitation-19654074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19654074 |
| http://purl.uniprot.org/uniprot/#_A0A0A0WB88-mappedCitation-19654074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19654074 |