| http://purl.uniprot.org/citations/19654407 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19654407 | http://www.w3.org/2000/01/rdf-schema#comment | "The polymorphic products of major histocompatibility complex class I-related chain A (MICA) genes are important in solid organ transplantation rejection. MICA expression is limited to gut epithelium and may play a role in triggering acute graft-versus-host disease (aGVHD). A total of 236 recipients of unrelated donor transplantation were studied. Donor-recipient human leukocyte antigen (HLA) match was 10/10 human leukocyte antigen (HLA-A, -B, -C, -DRB1, -DQB1) in 73% and MICA mismatch in 8.4%. Because of physical vicinity of the loci, MICA mismatch was significantly associated with mismatch at HLA-B and HLA-C. A higher rate of grade II-IV aGVHD was seen in MICA-mismatched patients (80% vs 40%, P = .003) irrespective of degree of HLA matching (HLA 10/10 match: 75% vs 39%, P = .02) and HLA any mismatch (83% vs 46%, P = .003). The rate of grade II-IV gastrointestinal aGVHD was also higher in MICA-mismatched patients (35% vs 17%, P = .05). We conclude that MICA may represent novel a transplantation antigen recognized by human allogeneic T cells. This study was registered at ClinicalTrials.gov (Identifier NCT00506922)."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.org/dc/terms/identifier | "doi:10.1182/blood-2009-05-223172"xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Liu P."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Zou Y."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Kebriaei P."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Parmar S."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Stastny P."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Cano P."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Fernandez-Vina M."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Pesoa S."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Shpall E.J."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Champlin R.E."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Del Lima M."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Giralt S."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Hosing C."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Patah P.A."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Popat U."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Qazilbash M.H."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "Rondon G."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/author | "de Padua Silva L."xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/name | "Blood"xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/pages | "2884-2887"xsd:string |
| http://purl.uniprot.org/citations/19654407 | http://purl.uniprot.org/core/title | "Donor-recipient mismatches in MHC class I chain-related gene A in unrelated donor transplantation lead to increased incidence of acute graft-versus-host disease."xsd:string |