| http://purl.uniprot.org/citations/19663695 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19663695 | http://www.w3.org/2000/01/rdf-schema#comment | "Interleukin-14alpha is cytokine encoded by the plus strand of il-14 gene using exons 3-10. It has been demonstrated in an IL-14-transgenic mice model that IL-14alpha could enhance an immune response to both TD and TI antigens and induce a phenotype that is very similar to SLE and Sjögren's syndrome, indicating that IL-14alpha may play an important role in autoimmune disease. To further study the role of IL-14alpha in human immune diseases, there is an urgent need to generate specific anti-human IL-14alpha monoclonal antibodies. In this study, we immunized BALB/c mice with synthesized human IL-14alpha-C polypeptide and obtained a novel monoclonal antibody, the anti-IL-14alpha-C antibody. Analysis by enzyme-linked immunosorbent assay (ELISA), spot-ELISA, Western blot, and immuoprecipitation revealed that the MAb were specifically against recombinant human IL-14alpha protein, and its subtype and affinity constant (K(aff)) were IgG2a/kappa and 1.007 x 10(8) M(-1), respectively. This antibody might facilitate studies for pathophysiology of autoimmune disease."xsd:string |
| http://purl.uniprot.org/citations/19663695 | http://purl.org/dc/terms/identifier | "doi:10.1089/hyb.2009.0007"xsd:string |
| http://purl.uniprot.org/citations/19663695 | http://purl.uniprot.org/core/author | "Luo Z."xsd:string |
| http://purl.uniprot.org/citations/19663695 | http://purl.uniprot.org/core/author | "Peng X."xsd:string |
| http://purl.uniprot.org/citations/19663695 | http://purl.uniprot.org/core/author | "Zhang C."xsd:string |
| http://purl.uniprot.org/citations/19663695 | http://purl.uniprot.org/core/author | "Zhou C."xsd:string |
| http://purl.uniprot.org/citations/19663695 | http://purl.uniprot.org/core/author | "Wei D."xsd:string |
| http://purl.uniprot.org/citations/19663695 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19663695 | http://purl.uniprot.org/core/name | "Hybridoma (Larchmt)"xsd:string |
| http://purl.uniprot.org/citations/19663695 | http://purl.uniprot.org/core/pages | "235-239"xsd:string |
| http://purl.uniprot.org/citations/19663695 | http://purl.uniprot.org/core/title | "Characteristics of a novel monoclonal antibody against interleukin-14alpha."xsd:string |
| http://purl.uniprot.org/citations/19663695 | http://purl.uniprot.org/core/volume | "28"xsd:string |
| http://purl.uniprot.org/citations/19663695 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19663695 |
| http://purl.uniprot.org/citations/19663695 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19663695 |
| http://purl.uniprot.org/uniprot/#_A0AUK0-mappedCitation-19663695 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19663695 |
| http://purl.uniprot.org/uniprot/#_P40222-mappedCitation-19663695 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19663695 |
| http://purl.uniprot.org/uniprot/#_Q3UXT5-mappedCitation-19663695 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19663695 |
| http://purl.uniprot.org/uniprot/#_Q3UD58-mappedCitation-19663695 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19663695 |
| http://purl.uniprot.org/uniprot/#_Q6PAM1-mappedCitation-19663695 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19663695 |
| http://purl.uniprot.org/uniprot/#_Q69YT3-mappedCitation-19663695 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19663695 |
| http://purl.uniprot.org/uniprot/#_Q8C5K1-mappedCitation-19663695 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19663695 |
| http://purl.uniprot.org/uniprot/P40222 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19663695 |
| http://purl.uniprot.org/uniprot/Q69YT3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19663695 |
| http://purl.uniprot.org/uniprot/Q3UXT5 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19663695 |