| http://purl.uniprot.org/citations/19674023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19674023 | http://www.w3.org/2000/01/rdf-schema#comment | "AimThe aim of this study was to study the association between the HLA-DRB1 alleles and the clinical course of ulcerative colitis (UC).Method Seventy-five Mexican patients with UC were studied. High resolution HLA typing was performed using Polymerase Chain Reaction-Sequence Specific Oligonucleotide PCR-SSO reverse dot blot and Polymerase Chain Reaction-single specific primer PCR-SSP. Molecular typing techniques were applied to define HLA-DRB1 alleles.ResultsSeventy-five patients (36 female patients, 39 male patients) were studied. Significant associations were found between some HLA-DRB1 alleles and the clinical course of disease: initial active and then inactive and the HLA-DRB1*14 allele (P = 0.03; OR = 4.63; 95% CI: 1.08-21.23); and HLA-DRB1*08 allele (P = 0.04; OR = 4.34; 95% CI: 1.9-33.3). On the other hand, the HLA-DRB1*07 (P = 0.001; OR = 9.76 95% CI: 1.55-65.56) was significantly associated with steroid dependence in UC patients.Conclusions This study suggests that HLA-DRB1 alleles were associated with the clinical course of disease and steroid dependence in UC patients."xsd:string |
| http://purl.uniprot.org/citations/19674023 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1463-1318.2009.02025.x"xsd:string |
| http://purl.uniprot.org/citations/19674023 | http://purl.uniprot.org/core/author | "Granados J."xsd:string |
| http://purl.uniprot.org/citations/19674023 | http://purl.uniprot.org/core/author | "Yamamoto-Furusho J.K."xsd:string |
| http://purl.uniprot.org/citations/19674023 | http://purl.uniprot.org/core/author | "Rodriguez-Bores L."xsd:string |
| http://purl.uniprot.org/citations/19674023 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/19674023 | http://purl.uniprot.org/core/name | "Colorectal Dis"xsd:string |
| http://purl.uniprot.org/citations/19674023 | http://purl.uniprot.org/core/pages | "1231-1235"xsd:string |
| http://purl.uniprot.org/citations/19674023 | http://purl.uniprot.org/core/title | "HLA-DRB1 alleles are associated with the clinical course of disease and steroid dependence in Mexican patients with ulcerative colitis."xsd:string |
| http://purl.uniprot.org/citations/19674023 | http://purl.uniprot.org/core/volume | "12"xsd:string |
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