| http://purl.uniprot.org/citations/19682430 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19682430 | http://www.w3.org/2000/01/rdf-schema#comment | "MicroRNAs are involved in cancer-related processes. The microRNA-21(miR-21) has been identified as the only miRNA over-expressed in a wide variety of cancers, including cervical cancer. However, the function of miR-21 is unknown in cervical carcinomas. In this study, we found that the inhibition of miR-21 in HeLa cervical cancer cells caused profound suppression of cell proliferation, and up-regulated the expression of the tumor suppressor gene PDCD4. We also provide direct evidence that PDCD4-3'UTR is a functional target of miR-21 and that the 18bp putative target site can function as the sole regulatory element in HeLa cells. These results suggest that miR-21 may play an oncogenic role in the cellular processes of cervical cancer and may serve as a target for effective therapies."xsd:string |
| http://purl.uniprot.org/citations/19682430 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2009.08.044"xsd:string |
| http://purl.uniprot.org/citations/19682430 | http://purl.uniprot.org/core/author | "Xu H."xsd:string |
| http://purl.uniprot.org/citations/19682430 | http://purl.uniprot.org/core/author | "Zhou H."xsd:string |
| http://purl.uniprot.org/citations/19682430 | http://purl.uniprot.org/core/author | "Yao Q."xsd:string |
| http://purl.uniprot.org/citations/19682430 | http://purl.uniprot.org/core/author | "Qu L.H."xsd:string |
| http://purl.uniprot.org/citations/19682430 | http://purl.uniprot.org/core/author | "Zhang Q.Q."xsd:string |
| http://purl.uniprot.org/citations/19682430 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19682430 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/19682430 | http://purl.uniprot.org/core/pages | "539-542"xsd:string |
| http://purl.uniprot.org/citations/19682430 | http://purl.uniprot.org/core/title | "MicroRNA-21 promotes cell proliferation and down-regulates the expression of programmed cell death 4 (PDCD4) in HeLa cervical carcinoma cells."xsd:string |
| http://purl.uniprot.org/citations/19682430 | http://purl.uniprot.org/core/volume | "388"xsd:string |
| http://purl.uniprot.org/citations/19682430 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19682430 |
| http://purl.uniprot.org/citations/19682430 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19682430 |
| http://purl.uniprot.org/uniprot/#_B4DKX4-mappedCitation-19682430 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19682430 |
| http://purl.uniprot.org/uniprot/#_B2R6E2-mappedCitation-19682430 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19682430 |
| http://purl.uniprot.org/uniprot/#_Q53EL6-mappedCitation-19682430 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19682430 |
| http://purl.uniprot.org/uniprot/Q53EL6 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19682430 |
| http://purl.uniprot.org/uniprot/B2R6E2 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19682430 |
| http://purl.uniprot.org/uniprot/B4DKX4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19682430 |